Stereoselective Preparation of C-Aryl Glycosides via Visible-Light- Induced Nickel-Catalyzed Reductive Cross-Coupling of Glycosyl Chlorides and Aryl Bromides
Stereoselective Preparation of C-Aryl Glycosides via Visible-Light- Induced Nickel-Catalyzed Reductive Cross-Coupling of Glycosyl Chlorides and Aryl Bromides
复制标题
通过可见光诱导镍催化糖基氯和芳基溴的还原交叉偶联立体选择性制备 C-芳基糖苷
DOI：
10.1002/adsc.202100343
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发表时间：
2021
影响因子：
5.4
通讯作者：
Dawen Niu
中科院分区：
文献类型：
--
作者：
Ze-Dong Mou;Jia-Xi Wang;Xia Zhang;Dawen Niu
已经开发了糖基氯与芳基溴的镍催化的交叉偶联反应。该反应在可见光照射下顺利进行，并使用了工作台稳定的糖基氯化物，允许高度立体选择性地合成C-芳基糖苷。
A nickel‐catalyzed cross‐coupling reaction of glycosyl chlorides with aryl bromides has been developed. The reaction proceeds smoothly under visible‐light irradiation and features the use of bench‐stable glycosyl chlorides, allowing the highly stereoselective synthesis ofC‐aryl glycosides.