Somatotopic organization of forelimb representation in cervical enlargement of raccoon dorsal horn.
Somatotopic organization of forelimb representation in cervical enlargement of raccoon dorsal horn.
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浣熊背角颈部增大中前肢表征的体位组织。
DOI：
10.1152/jn.1989.61.1.126
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发表时间：
1989
影响因子：
2.5
通讯作者：
West-Johnsrud,L
中科院分区：
文献类型：
--
作者：
PubolsJr,BH;Hirata,H;West-Johnsrud,L
1.在13只戊巴比妥钠麻醉的北美浣熊上，研究了前肢在脊髓C5-T2节段背角的体感代表。在总共504个位点记录了对光机械刺激的单单位或多单位反应，随后从染色的横截面重建。从这些，背视图地图的前肢表示在Rexed的椎板III和IV的合成。2.有一个移位，串行重叠的代表性的不同前肢地区的rostrocaudal和mediolateral轴的背角。感受野的rostrocaudal进展是从轴前前肢，前爪，轴后前肢，而mediolateral进展是从掌侧无毛前爪向躯干。3.手指和手掌垫的无毛表面的代表表现出相当大的重叠，与手指的代表延伸更横向，但手掌的代表延伸更吻和尾。三分之一的所有记录位点专门用于无毛的皮肤表示。4.与浣熊早期研究结果的比较表明，一个给定的数字或手掌垫的代表性更受限制的rostrocaudal程度在背角比在背根，而且，与各种核区域的背柱内侧丘系系统，无毛表面的前爪在背角代表不足。5.结果表明，在背角中存在前肢表征的背腹模块化组织。这些楔形模块来自较大的集合体，代表主要的身体细分，并在吻尾向弯曲。
1. Somatosensory representation of the forelimb in the dorsal horn of spinal segments C5-T2 was examined in 13 North American raccoons anesthetized with pentobarbital sodium. Single- or multiple-unit responses to light mechanical stimulation were recorded at a total of 504 loci, which were subsequently reconstructed from stained, transverse sections. From these, dorsal view maps of forelimb representation in Rexed's laminae III and IV were synthesized. 2. There was a shifting, serial overlap of representations of different forelimb regions in both the rostrocaudal and mediolateral axes of the dorsal horn. The rostrocaudal progression of receptive fields was from preaxial forelimb to forepaw to postaxial forelimb, whereas the mediolateral progression was from the volar glabrous forepaw toward the trunk. 3. Representations of the glabrous surfaces of the digits and palm pads showed considerable overlap, with the digital representations extending more laterally, but the palmar representations extending more rostrally and caudally. One-third of all recording loci were devoted exclusively to glabrous skin representation. 4. Comparison with results of earlier studies in raccoons indicates that representation of a given digit or palm pad is more restricted in rostrocaudal extent in the dorsal horn than in the dorsal roots, and that, compared with various nuclear regions of the dorsal column-medial lemniscal system, the glabrous surfaces of the forepaw are underrepresented in the dorsal horn. 5. The results suggest that there is a dorsoventral modular organization of forelimb representation in the dorsal horn. These wedge-shaped modules from larger aggregates which represent major body subdivisions and which course sinuously in the rostrocaudal dimension.