Prognostic factors in arthrocentesis of the temporomandibular joint: Comparison of bradykinin, leukotriene B4, prostaglandin E2, and substance P level in synovial fluid between successful and unsuccessful cases
Prognostic factors in arthrocentesis of the temporomandibular joint: Comparison of bradykinin, leukotriene B4, prostaglandin E2, and substance P level in synovial fluid between successful and unsuccessful cases
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DOI：
10.1016/j.joms.2005.10.068
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发表时间：
2007-02-01
影响因子：
1.9
通讯作者：
Yoshimura, Hiroshi
中科院分区：
文献类型：
--
作者：
Kaneyama, Keiseki;Segami, Natsuki;Yoshimura, Hiroshi
目的：目的：比较颞下颌关节紊乱病（TMDs）关节穿刺术成功与失败患者血清缓激肽（BK）、白三烯B4（LTB 4）、前列腺素E2（PGE 2）和P物质（SP）水平的变化。在关节穿刺前从上级关节腔抽取关节液，用酶联免疫吸附法测定其BK、LTB 4、PGE 2和SP的浓度。结果：77%（51/66）的关节穿刺成功。LTB_4的平均检出率显著高于对照组（P
Purpose: To compare levels of bradykinin (BK), leukotriene B4 (LTB4), prostaglandin E2 (PGE2), and substance P (SP) between successful and unsuccessful cases of arthrocentesis of temporomandibular joint disorders (TMDs).Patients and Methods: A total of 66 joints in 66 patients with TMDs who underwent arthrocentesis were evaluated in this study. Synovial fluid diluted with saline solution was aspirated from the superior joint compartment before arthrocentesis and their concentrations of BK, LTB4, PGE2, and SP were determined by enzyme-linked immunosorbent assay. The differences in the detection rate and concentration of each mediator between successful cases and unsuccessful cases of arthrocentesis were analyzed statistically.Results: Arthrocentesis was successful for 77% (51/66) of the joints. The mean detection rate of LTB4 was significantly (P