Wound heating: Immunological aspects
Wound heating: Immunological aspects
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DOI：
10.1016/j.injury.2006.02.035
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发表时间：
2006-04-01
影响因子：
2.5
通讯作者：
Moutsopoulos, Haralampos M.
中科院分区：
文献类型：
--
作者：
Tsirogianni, Afrodite K.;Moutsopoulos, Niki Maria;Moutsopoulos, Haralampos M.
伤口加热是一个复杂的生物过程，由一系列旨在修复受损组织的连续事件组成。免疫系统在这一过程中的作用不仅是识别和对抗损伤部位新出现的抗原，而且还参与受损区域的清创并有助于加热过程。在这篇综述中，我们讨论了参与组织修复的免疫系统的分子和细胞。我们描述了初始损伤过程中的免疫识别机制以及对损伤的先天性和适应性免疫反应。最后，我们讨论了免疫系统在再生和修复中的作用。(C)2006爱思唯尔有限公司保留所有权利。
Wound heating is a complex biological process, comprised of a series of a sequential events aiming to repair injured tissue. The role of the immune system in this process is not only to recognise and combat the newly presented antigens at the site of injury, but also to participate in the debridement of the damaged area and to contribute to the process of heating. In this review, we discuss the molecules and cells of the immune system that participate in tissue repair. We describe the mechanisms of immune recognition during initial insult and the innate and adaptive immune responses to injury. Finally, we address the role of the immune system in regeneration and repair. (C) 2006 Elsevier Ltd. All rights reserved.