Epidemiology and classification of perinatal stroke
Epidemiology and classification of perinatal stroke
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DOI：
10.1016/j.siny.2009.07.001
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发表时间：
2009-10-01
影响因子：
3
通讯作者：
Lynch, John Kylan
中科院分区：
文献类型：
--
作者：
Lynch, John Kylan
中风是婴儿和儿童死亡和慢性发病的重要原因。根据临床和实验室标准，围产期卒中的病例定义因研究而异。美国国立卫生研究院最近举办的围产期卒中研讨会就围产期卒中的定义和分类提供了共识建议。据估计，每 1600 至 5000 名新生儿中就有 1 人发生围产期中风。围产期中风的临床表现取决于诊断时间，急性或迟发性，但大多数会出现癫痫发作。围产期卒中的危险因素尚未得到充分研究。据报道，患有围产期卒中的婴儿会出现多种孕产妇和新生儿疾病。患有围产期中风的儿童通常会出现长期残疾，包括运动缺陷、认知和行为障碍以及癫痫。超过一半的人会出现长期的运动或认知问题，围产期卒中后的复发率非常低。 (c) 2009 年，爱思唯尔有限公司出版。
Stroke is an important cause of mortality and chronic morbidity in infants and children. Case definitions for perinatal stroke have varied among studies by clinical and laboratory criteria. A recent US National Institutes of Health workshop on perinatal stroke provided consensus recommendations on the definition and classification of perinatal stroke. The incidence of perinatal stroke has been estimated at 1 in 1600 to 5000 births. The clinical presentation of perinatal stroke depends on the time of diagnosis, acute or delayed, but most will present with seizures. Risk factors for perinatal stroke have not been well studied. Several maternal and neonatal disorders have been reported in infants with perinatal stroke. Children who suffer perinatal stroke typically develop long-term disabilities including motor deficits, cognitive and behavioral disorders, and epilepsy. More than half will develop long-term motor or cognitive problems and the recurrence rate after perinatal stroke is very low. (c) 2009 Published by Elsevier Ltd.