LEPTOSPIRAL INFECTION IN SCHOOL-CHILDREN FROM TRINIDAD AND BARBADOS
LEPTOSPIRAL INFECTION IN SCHOOL-CHILDREN FROM TRINIDAD AND BARBADOS
复制标题
DOI：
10.1017/s0950268800030442
复制
发表时间：
1989-08-01
影响因子：
4.2
通讯作者：
EDWARDS, CN
中科院分区：
文献类型：
--
作者：
EVERARD, COR;HAYES, RJ;EDWARDS, CN
1980年至1983年，对500多名7~14岁巴巴迪亚和500名特里斯坦学龄儿童进行了钩端螺旋体凝集素血清学调查。这些孩子是从城市和农村的学校中随机挑选出来的，大约每年一次，检查三次。用显微镜凝集试验，总共有12.5%的巴巴迪亚儿童和9.5%的特里迪亚儿童的血清效价为50。在这两个岛屿上，男性的血清阳性率高于女性，这一差异在农村学校尤为明显。没有证据表明城市和农村学校之间或初中和中学年龄段之间的流行率存在差异。血清学与社会经济和行为因素的关联分析显示，特立尼达与S父亲的职业有显著关联，但两岛的大多数其他变量仅显示微弱的非显著关联。特立尼达的14名儿童和巴巴多斯的3名儿童血清转换。特立尼达以每年1.6%的速度发生血清转换，与牲畜接触和没有自来水供应显著相关。在特立尼达，秋季是最常见的血清群，但这只占血清阳性的不到四分之一。在巴巴多斯，巴拿马占血清阳性者的一半以上，其发病率约为第二个最常见的血清组--秋季血型的四倍。在巴巴多斯，1979年11月至1986年12月期间，有39名19岁或以下的人因钩端螺旋体病住院。5~9岁、10~14岁和15~19岁年龄组年平均发病率分别为2.2/10万、4.9/10万和13.3/10万。
A serological survey for leptospiral agglutinins was undertaken between 1980 and 1983 in over 500 Barbadian and 500 Trinidadian school-children aged 7-14 years. The children were selected randomly from urban and rural schools, and examined three times at approximately annual intervals. A total of 12.5% of the Barbadian children and 9.5% of the Trinidadian children were seropositive at a titre of 50 using the microscopic agglutination test. On both islands, seroprevalence was higher in males than females, the difference being significant in rural schools. There was no evidence of a difference in prevalence between urban and rural schools, or between junior and secondary age-ranges. Analysis of the association of serology with socio-economic and behavioural factors showed a significant association in Trinidad with father''s occupation, but most other variables on both islands showed only weak non-significant associations. Fourteen children in Trinidad and three Barbados seroconverted. Seroconversion in Trinidad occurred at a rate of 1.6% per annum and was significantly associated with livestock contact and with absence of a tapped water supply. In Trinidad, Autumnalis was the most commonly recorded serogroup, but this accounted for less than a quarter of seropositives. In Barbados, Panama accounted for over half the seropositives and was about four times more common than the next most common serogroup, Autumnalis. In Barbados, 39 persons aged 19 or less were hospitalized with leptospirosis between November 1979 and December 1986. Average annual incidence rates were 2.2, 4.9 and 13.3 per 100,000 in the 5-9, 10-14 and 15-19 age-groups, respectively.