External-stimuli responsive systems for cancer theranostic
External-stimuli responsive systems for cancer theranostic
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DOI：
10.1016/j.ajps.2016.06.001
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发表时间：
2016-10
影响因子：
10.2
通讯作者：
Jianhui Yao;Jingxian Feng;Jun Chen
中科院分区：
文献类型：
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作者：
Jianhui Yao;Jingxian Feng;Jun Chen
新型纳米材料和纳米技术的兴起激发了研究人员的灵感，他们正在努力设计更安全，更有效的药物输送系统用于癌症治疗。刺激响应型纳米材料因其时空可控的特性，为设计可控的药物传递系统提供了一种新的途径。此外，外部刺激（光、磁场和超声）由于其独特的特性，可以发展成为个性化医疗的治疗诊断应用。在这篇综述中，我们给出了一个简短的概述，在过去几年中，已被广泛研究的药物输送和治疗诊断学的某些外部刺激响应系统的重大进展和挑战。
The upsurge of novel nanomaterials and nanotechnologies has inspired the researchers who are striving for designing safer and more efficient drug delivery systems for cancer therapy. Stimuli responsive nanomaterial offered an alternative to design controllable drug delivery system on account of its spatiotemporally controllable properties. Additionally, external stimuli (light, magnetic field and ultrasound) could develop into theranostic applications for personalized medicine use because of their unique characteristics. In this review, we give a brief overview about the significant progresses and challenges of certain external-stimuli responsive systems that have been extensively investigated in drug delivery and theranostics within the last few years.