Relationship of race-, sexual orientation-, and HIV-related discrimination with adherence to HIV treatment: a pilot study
Relationship of race-, sexual orientation-, and HIV-related discrimination with adherence to HIV treatment: a pilot study
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DOI：
10.1007/s10865-008-9169-0
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发表时间：
2008-10-01
影响因子：
3.1
通讯作者：
Delahanty, Douglas L.
中科院分区：
文献类型：
--
作者：
Boarts, Jessica M.;Bogart, Laura M.;Delahanty, Douglas L.
必须接近完美地坚持高效抗逆转录病毒治疗 (HAART)，才能维持对 HIV 病毒载量的抑制，并防止 HIV 耐药株的发展。艾滋病毒感染者 (PLWH) 经常报告依从性较低。与依从性差相关的一个变量是感知歧视。然而，研究一般没有考虑不同类型的歧视对依从性可能产生的独特影响。本试点研究旨在调查三种类型的歧视（由于 HIV+ 状况、种族或性取向）与 57 名感染者中的依从性之间的关系。进行逻辑回归分析以证明每种类型的歧视与自我报告的依从性之间的关系。种族歧视显着预示着依从性较低，而性取向和艾滋病毒相关歧视则不然。结果强调了在设计干预措施以提高 HAART 依从性时解决歧视问题（特别是种族问题）的重要性。
Adherence to highly active antiretroviral therapy (HAART) must be close to perfect in order to maintain suppression of HIV viral load, and to prevent the development of drug resistant strains of HIV. People living with HIV (PLWH) often report low levels of adherence. One variable that has been linked to poor adherence is perceived discrimination; however, research has generally not considered the possible unique effects of different types of discrimination on adherence. The present pilot study aimed to examine the association of three types of discrimination (due to HIV+ status, race, or sexual orientation) with adherence among 57 PLWH. Logistic regression analyses were conducted to demonstrate the relationships between each type of discrimination and self-reported adherence. Racial discrimination significantly predicted lower adherence levels, whereas sexual orientation- and HIV-related discrimination did not. Results underscore the importance of addressing discrimination issues, specifically racial, when designing interventions to improve adherence to HAART.