Natural history of microprolactinomas: six-year follow-up.
Natural history of microprolactinomas: six-year follow-up.
复制标题
泌乳素微瘤的自然史：六年随访。
DOI：
10.1227/00006123-198302000-00008
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发表时间：
1983
期刊：
影响因子：
4.8
通讯作者：
Charles M. March
中科院分区：
文献类型：
--
作者：
Martin H. Weiss;James S. Teal;P. S. Gott;Robert R. Wycoff;Richard Yadley;M. Apuzzo;S. Giannotta;O. Kletzky;Charles M. March
对微泌乳素瘤患者的6年随访表明，很少有患者（27例中有3例）在此期间显示肿瘤显著生长。未接受治疗的此类患者的主要危害似乎是在持续高催乳素血症的情况下发生过早骨质疏松症的风险。这种并发症的风险可能超过选定患者的早期手术干预的风险。这种短期的肿瘤生长风险（约10%）必须在决定治疗努力时加以权衡。
A 6-year follow-up of patients harboring microprolactinomas suggests that few patients (3 of 27) demonstrate significant growth of their tumor during this time. The major hazard for such patients who are not treated seems to be their risk for the development of premature osteoporosis in the face of sustained hyperprolactinemia. The risks of this complication may exceed the risks of early surgical intervention in selected patients. This short term risk of tumor growth (about 10%) must be weighed in the decision about therapeutic endeavors.