Anti-brucellaantibodies in blood donors in Boushehr, Iran.
Anti-brucellaantibodies in blood donors in Boushehr, Iran.
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DOI：
10.1007/s00580-007-0685-z
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发表时间：
2008-01-01
影响因子：
--
通讯作者：
Salehi, T. Z.
中科院分区：
文献类型：
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作者：
Khorasgani, M. R.;Esmaeili, H.;Salehi, T. Z.
布鲁氏菌病是世界范围内的一个主要健康问题，特别是在发展中国家。这是伊朗的一种流行病。布鲁氏菌病主要通过直接接触受感染的动物或其产品传播给人类。然而，这些生物体也可以通过输入受感染的血液传播。在这项研究中，我们确定了布希尔志愿献血者中布鲁氏菌病的血清学患病率。总共有10，500名献血者接受了布鲁氏菌感染血清学证据的筛查。使用虎红平板试验（RBPT）。为确认RBPT阳性结果，进行了标准试管凝集试验（STAT）和2-巯基乙醇试验（2 ME）。在伊朗Boushehr省10，500份献血员血清中，用RBPT和STAT分别检测到0.076%和0.057%的抗布鲁氏菌抗体。仅1份样本的2 ME试验在低滴度（1/20）下呈阳性。
Brucellosis is a major health problem worldwide especially in developing countries. It is an endemic disease in Iran. The transmission of brucellosis to man is primarily by direct contact with infected animals or their products. However, the organisms can also be transmitted by transfusion of infected blood. In this study, we determined serological prevalence of brucellosis among volunteer blood donors in Boushehr. A total of 10,500 blood donors were screened for serological evidence of infection withbrucellaspp. using the Rose Bengal plate test (RBPT). To confirm positive RBPT results, a standard tube agglutination test (STAT) and a 2-mercaptoethanol test (2ME) were performed. Of the 10,500 serum samples from blood donors in Boushehr province, Iran, we found anti-brucellaantibodies in 0.076 and 0.057% sera samples with RBPT and STAT, respectively. The 2ME test was positive at low titer (1/20) in one sample only.