The deficit of the isometric tetanic tension redeveloped after a release of frog muscle at a constant velocity
The deficit of the isometric tetanic tension redeveloped after a release of frog muscle at a constant velocity
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等速释放青蛙肌肉后，等长强直张力的缺陷重新出现
DOI：
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发表时间：
1979
期刊：
影响因子：
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通讯作者：
L. Plaghki
中科院分区：
文献类型：
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作者：
G. Maréchal;L. Plaghki
等距收缩的蛙缝缝肌以恒定速度从长度lL到lS释放（δ l = lL -lS， lS大于lO）。释放后重新形成的张力PS低于LS点的等距张力PS，高于lL点的等距张力PL。张力亏损D定义为PS-PS之差。破伤风期间释放的时间不影响D。D/PO与δ l/lO成正比。当释放速度为2.5 mm/s时，比例常数k = 1.35 +/- 0.19 （n = 8）。当肌肉以同样的速度释放时，我们发现D是速度的指数递减函数。在lS小于lO的区域也存在张力缺陷。比例常数k较小，但释放速度对D的影响没有改变。在释放过程中，当释放速度改变时，D也随之改变，表明l和V的作用是相乘的。这些事实提出了一个可行的假设，该假设基于这样的概念，即在释放过程中进入重叠区域的肌动蛋白丝受到强直应力的拉伸，因此无法形成正常的交叉桥。
Frog sartorius muscles tetanized isometrically were released at a constant velocity from lengths lL to lS (delta l = lL -lS; Ls greater than lO). The tension PS redeveloped after the release was lower than the isometric tension PS at LS, and higher than the isometric tension PL at lL. The tension deficit D is defined as the difference PS-PS. The timing of the release during the tetanus did not influence D. D/PO was proportional to delta l/lO. The proportionality constant k was equal to 1.35 +/- 0.19 (n = 8) when the velocity of release was 2.5 mm/s. When the muscles were released the same delta l, D was found to be an exponential decreasing function of the velocity. The tension deficit was also found in experiments performed in the region lS less than lO. The proportionality constant k was smaller, but the influence of the velocity of the release on D was not modified. When the velocity of the release was changed during the release, D changed accordingly, showing that the effects of delta l and V are multiplicative. These facts suggest a working hypothesis based on the concept that the actin filaments which enter the overlap region during a release are strained by the tetanic stress and therefore unable to make normal cross-bridges.