Anti-infectious Activity of Tryptophan Metabolites in the L-Tryptophan-L-Kynurenine Pathway
Anti-infectious Activity of Tryptophan Metabolites in the L-Tryptophan-L-Kynurenine Pathway
复制标题
DOI：
10.1248/bpb.32.41
复制
发表时间：
2009-01-01
影响因子：
2
通讯作者：
Sasatsu, Masanori
中科院分区：
文献类型：
--
作者：
Narui, Koji;Noguchi, Norihisa;Sasatsu, Masanori
为研究同种异体血管移植物的抗感染作用，测定了吲哚乙胺2，3-双加氧酶介导的色氨酸代谢产物的抗菌活性。无论色氨酸是否存在，移植后血管提取液中耐甲氧西林金黄色葡萄球菌(M RSA)在10h以上的生长速度均明显慢于未移植血管的提取液(P
To study the anti-infectious effect of a vascular allograft, the antimicrobial activity of tryptophan metabolites mediated by indoleamine 2,3-dioxygenase was determined. The growth of methicillin-resistant Staphylococcus aureus (M RSA) over 10 h in extracts from post-transplantation vascular allograft was significantly slower than that of extracts from non-transplantation vascular allograft regardless of the presence of tryptophan (p