The UCSC Genome Browser.
The UCSC Genome Browser.
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DOI：
10.1002/0471250953.bi0104s40
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发表时间：
2011-10-01
影响因子：
--
通讯作者：
Kent, W James
中科院分区：
文献类型：
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作者：
Karolchik, Donna;Hinrichs, Angie S;Kent, W James
加州大学圣克鲁斯分校(UCSC)基因组浏览器是一种流行的基于网络的工具，用于以任何比例快速显示所需的基因组部分，并伴随着一系列对齐的注释“轨迹”。UCSC基因组生物信息学小组和外部合作者生成的注释包括基因预测、mRNA和表达序列标签比对、简单核苷酸多态、表达和调控数据、表型和变异数据，以及成对和多物种比较基因组学数据。与一个地区有关的所有信息都集中在一个窗口中，便于生物分析和解释。Genome浏览器轨迹下的数据库表可以使用另一个基于Web的应用程序UCSC Table Browser来查看、下载和操作。用户可以在两个浏览器中上传各种格式的个人数据集作为自定义注释轨道，用于研究或教育目的。本单元介绍如何使用基因组浏览器和表格浏览器进行基因组分析，下载底层数据库表，以及创建和显示定制的注释轨迹。加州大学圣克鲁斯分校(UCSC)基因组浏览器是一个流行的基于网络的工具，用于以任何比例快速显示所需的基因组部分，并伴随着一系列对齐的注释“轨迹”。UCSC基因组生物信息学小组和外部合作者生成的注释包括基因预测、mRNA和表达序列标签比对、简单核苷酸多态、表达和调控数据、表型和变异数据，以及成对和多物种比较基因组学数据。与一个地区有关的所有信息都集中在一个窗口中，便于生物分析和解释。Genome浏览器轨迹下的数据库表可以使用另一个基于Web的应用程序UCSC Table Browser来查看、下载和操作。用户可以在两个浏览器中上传各种格式的个人数据集作为自定义注释轨道，用于研究或教育目的。本单元介绍如何使用Genome Browser和Table Browser进行基因组分析、下载底层数据库表以及创建和显示定制注释轨迹。
The University of California Santa Cruz (UCSC) Genome Browser is a popular Web-based tool for quickly displaying a requested portion of a genome at any scale, accompanied by a series of aligned annotation "tracks." The annotations generated by the UCSC Genome Bioinformatics Group and external collaborators include gene predictions, mRNA and expressed sequence tag alignments, simple nucleotide polymorphisms, expression and regulatory data, phenotype and variation data, and pairwise and multiple-species comparative genomics data. All information relevant to a region is presented in one window, facilitating biological analysis and interpretation. The database tables underlying the Genome Browser tracks can be viewed, downloaded, and manipulated using another Web-based application, the UCSC Table Browser. Users can upload personal datasets in a wide variety of formats as custom annotation tracks in both browsers for research or educational purposes. This unit describes how to use the Genome Browser and Table Browser for genome analysis, download the underlying database tables, and create and display custom annotation tracks.The University of California Santa Cruz (UCSC) Genome Browser is a popular Web-based tool for quickly displaying a requested portion of a genome at any scale, accompanied by a series of aligned annotation "tracks." The annotations generated by the UCSC Genome Bioinformatics Group and external collaborators include gene predictions, mRNA and expressed sequence tag alignments, simple nucleotide polymorphisms, expression and regulatory data, phenotype and variation data, and pairwise and multiple-species comparative genomics data. All information relevant to a region is presented in one window, facilitating biological analysis and interpretation. The database tables underlying the Genome Browser tracks can be viewed, downloaded, and manipulated using another Web-based application, the UCSC Table Browser. Users can upload personal datasets in a wide variety of formats as custom annotation tracks in both browsers for research or educational purposes. This unit describes how to use the Genome Browser and Table Browser for genome analysis, download the underlying database tables, and create and display custom annotation tracks.