Cutis verticis gyrata: Unusual chloromatous disease in acute myelogenous leukemia
Cutis verticis gyrata: Unusual chloromatous disease in acute myelogenous leukemia
复制标题
旋转性头晕：急性髓性白血病中罕见的绿色瘤病
DOI：
10.1002/ajh.2830080411
复制
发表时间：
1980
影响因子：
12.8
通讯作者：
R. M. Christiansen
中科院分区：
文献类型：
--
作者：
B. Cheson;R. M. Christiansen
绿瘤在急性或慢性粒细胞白血病患者中是一种罕见的发现。本文报告一例急性髓细胞白血病(AML)患者，其病程并发垂直回皮肤(CVG)、纵隔肿块、神经病变和因内脏受累而导致的肝脾肿大。白血病肿瘤和器官浸润的发展与他的血液学状况无关，并导致显著的发病率，并最终因消化道出血而死亡。然而，当这些并发症被作为白血病“庇护所”管理并进行局部放射治疗时，至少实现了对这些并发症的暂时控制。
Chloromas are an unusual finding in patients with acute or chronic granulocytic leukemia. The present report describes a man with acute myelogenous leukemia (AML) whose course was complicated by cutis verticis gyrata (CVG), a mediastinal mass, neuropathies, and hepatosplenomegaly as a result of visceral involvement. Leukemic tumors and organ infiltration developed independent of his hematologic status and resulted in significant morbidity and, eventually, mortality from gastrointestinal hemorrhage. Nevertheless, at least temporary control over these complications was achieved when they were managed as leukemic “sanctuaries” and treated with local irradiation.