EFFECT OF INCREASED KNEE-JOINT PRESSURE ON OXYGEN-TENSION AND BLOOD-FLOW IN SUBCHONDRAL BONE
EFFECT OF INCREASED KNEE-JOINT PRESSURE ON OXYGEN-TENSION AND BLOOD-FLOW IN SUBCHONDRAL BONE
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DOI：
10.1111/j.1748-1716.1984.tb07438.x
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发表时间：
1984-01-01
期刊：
影响因子：
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通讯作者：
SVALASTOGA, E
中科院分区：
文献类型：
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作者：
GRONLUND, J;KOFOED, H;SVALASTOGA, E
本文观察了家兔膝关节压力急性变化对亚慢性骨氧分压和局部血流量的影响。关节内的压力增加注入的NaCl溶液到关节腔中，和相关的变化，在软骨下O2张力测定质谱。质谱法用于检测局部血流的定性变化。当关节压力从习惯水平增加到75 mm Hg时，平均亚慢性O2张力从39至. apprx。30 mm Hg，同时，区域血流量显著减少。
The influence of acute changes in the knee joint pressure of rabbits on the O2 tension and the regional blood flow in the subchrondral bone was investigated. The intra-articular pressure was increased by infusion of a NaCl solution into the joint cavity, and the associated change in the subchondral O2 tension was measured by mas spectrometry. Mass spectrometry was used to detect qualitative changes in the regional blood flow. When joint pressure was increased from the habitual level to 75 mm Hg, the average subchrondral O2 tension was reduced from .apprx. 39 to .apprx. 30 mm Hg and, at the same time, the regional blood flow was reduced significantly.