A case-control study of the association between self-reported occupational and recreational physical activity and lung cancer
A case-control study of the association between self-reported occupational and recreational physical activity and lung cancer
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自我报告的职业和娱乐性体育活动与肺癌之间关系的病例对照研究
DOI：
10.1097/md.0000000000007923
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发表时间：
2017-09-01
期刊：
影响因子：
1.6
通讯作者：
Cai, Lin
中科院分区：
文献类型：
--
作者：
He, Fei;Chen, Li-mei;Cai, Lin
1 622例新诊断的肺癌患者和1 622例年龄、性别匹配的健康对照。高强度的职业体力活动与肺癌(OR=1.354，95%CI：1.068~1.717)，尤其是非小细胞肺癌(OR=1.384，95%CI：1.087~1.762)显著相关。中等或低强度的娱乐性体力活动与肺癌风险的降低有关。娱乐性体育活动的保护作用在现在或以前吸烟的人中观察到，但不在从不吸烟的人中观察到，在BMI正常或高的受试者中观察到，但在低BMI的受试者中观察到，以及没有慢性肺病病史的人。休闲体育活动的频率与肺癌风险的线性降低相关(P
This case-control study with a Fujian population investigated whether self-reported occupational and recreational physical activity may be associated with lung cancer.The population comprised 1622 patients with newly diagnosed primary lung cancer and 1622 age-and gender-matched healthy controls.High-intensity occupational physical activity was associated with significantly higher risk of lung cancer (OR=1.354, 95% CI: 1.068-1.717), especially nonsmall cell lung carcinoma (OR=1.384, 95% CI: 1.087-1.762). Moderate or low intensity recreational physical activity was associated with reduced risk of lung cancer. The protective effect of recreational physical activity was observed in current or former smokers, but not never-smokers, and in subjects with normal or high BMI, but not low BMI, as well as people without a history of chronic lung disease. The frequency of recreational physical activity was associated with a linear reduction in the risk of lung cancer (P