Clinical effects of exercise on subchondral bone of carpal and metacarpophalangeal joints in horses
Clinical effects of exercise on subchondral bone of carpal and metacarpophalangeal joints in horses
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DOI：
10.2460/ajvr.2000.61.1252
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发表时间：
2000-10-01
影响因子：
1
通讯作者：
Steyn, PS
中科院分区：
文献类型：
--
作者：
Kawcak, CE;McIlwraith, CW;Steyn, PS
为了确定踏车运动对2岁马的腕关节和掌指关节的软骨下骨的影响，动物：12匹健康的2岁马。运动组在高速跑台上跑5 d/wk，连续6个月。对照组的马被用手牵走相同的时间。结果的临床，放射学检查，核放射学，和计算机断层扫描检查，血清和滑膜浓度的骨代谢的生化标志物groups.Results-Exercised马显着跛脚在研究结束时比对照组马。在掌骨髁，但不是在腕关节的放射性核素摄取，是更大的行使马匹，与对照组相比。锻炼的马也有较高的subchonophone密度在掌骨髁比对照组的马，但这种差异没有检测到在腕骨。结论和临床相关性，没有评估的诊断技术是足够敏感的检测所有的骨软骨损伤。计算机断层扫描和计算机断层骨吸收测定法在检测小骨软骨碎片方面上级传统X线摄影。核素骨显像是软骨下骨改变的敏感指标，但在描述病变和区分正常骨重建与损伤方面缺乏特异性。较新的技术，如计算机断层扫描可以帮助临床医生更好地诊断早期和微妙的关节病变之前，马的发展严重的关节损伤。
Objective-To determine effects of treadmill exercise on subchondral bone of carpal and metacarpophalangeal joints of 2-year-old horses.Animals-12 healthy 2-year-old horses.Procedure-Horses were randomly assigned to the control (n = 6) or exercised (6) groups. Horses in the exercised group ran on a high-speed treadmill 5 d/wk for 6 months. Horses in the control group were hand walked for the same amount of time. Results of clinical, radiographic, nuclear scintigraphic, and computed tomographic examinations, and serum and synovial concentrations of biochemical markers of bone metabolism were compared between groups.Results-Exercised horses were significantly lamer at the end of the study than control horses. Radionuclide uptake in the metacarpal condyles, but not in the carpal joints, was greater in exercised horses, compared with control horses. Exercised horses also had a higher subchondral hone density in the metacarpal condyles than control horses, but such differences were not detected in the carpal bones.Conclusions and Clinical Relevance-None of the diagnostic techniques evaluated was sufficiently sensitive to detect all osteochondral damage. Computed tomography and computed tomographic osteoabsorptiometry were superior to conventional radiography for detecting small osteochondral fragments. Nuclear scintigraphy was a sensitive indicator of subchondral bone change but lacked specificity for describing lesions and discerning normal bone remodeling from damage. Newer techniques such as computed tomography may help clinicians better diagnose early and subtle joint lesions in horses prior to development of gross joint damage.