STRUCTURE OF COILED BETA-BETA-HAIRPINS AND BETA-BETA-CORNERS
STRUCTURE OF COILED BETA-BETA-HAIRPINS AND BETA-BETA-CORNERS
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DOI：
10.1016/0014-5793(91)80706-9
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发表时间：
1991-06-24
期刊：
影响因子：
3.5
通讯作者：
EFIMOV, AV
中科院分区：
文献类型：
--
作者：
EFIMOV, AV
本文考虑了两种类型的超二级结构：卷曲的β-β-发夹和β-β-角。β-β-角可以表示为在其自身上正交折叠的长β-β-发夹，使得链在从一层传递到另一层时围绕假想轴以右手方向旋转。它表明，β-β-发夹，形成一个卷曲的螺旋结构或β-β-角，是右手的，当从凹侧观察。在卷曲的β-β-发夹和β-β-角中β-链的这些独特排列在蛋白质建模和预测中具有特别的价值。
Two types of super-secondary structure, coiled beta-beta-hairpins and beta-beta-corners, are considered in this paper. A beta-beta-corner can be represented as a long beta-beta-hairpin folded orthogonally on itself so that the strands, when passing from one layer to the other, rotate in a right-handed direction about an imaginary axis. It is shown that a beta-beta-hairpin, forming a coiled coil structure or a beta-beta-corner, is right-handed when viewed from the concave side. These unique arrangements of beta-strands in the coiled beta-beta-hairpins and beta-beta-corners are of particular value in protein modelling and prediction.