Biofortification of pearl millet with iron and zinc in a randomized controlled trial increases absorption of these minerals above physiologic requirements in young children.
Biofortification of pearl millet with iron and zinc in a randomized controlled trial increases absorption of these minerals above physiologic requirements in young children.
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DOI：
10.3945/jn.113.176677
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发表时间：
2013-09
期刊：
影响因子：
--
通讯作者：
Hambidge KM
中科院分区：
文献类型：
--
作者：
Kodkany BS;Bellad RM;Mahantshetti NS;Westcott JE;Krebs NF;Kemp JF;Hambidge KM
小米具有不同寻常的抗旱性，因此这些谷物作为人类主食的使用逐渐增加，特别是在印度和撒哈拉以南非洲的大片地区。本研究的目的是确定铁和锌的吸收珍珠粟生物强化与2种微量营养素，通常缺乏非强化，植物性饮食全球。该研究在印度卡纳塔克邦的40名2岁儿童中进行（n = 21个试验组/19个对照组）。在0900 ~ 1600 h之间，每天喂3次试验餐，每餐提供1084 ± 17 g干珍珠小米粉，每天喂锌，每天喂铁。锌和铁的吸收量测定与建立稳定的同位素外源性标记技术和分析的重复饮食。试验组和对照组的铁吸收量分别为0.67 ± 0.48和0.23 ± 0.15mg/d（P < 0.001）。锌吸收量分别为0.95 ± 0.47和0.67 ± 0.24mg/d（P = 0.03）。这些数据不包括在3次测试餐之前和之后吃的零食中含有的适量铁和锌的吸收。总之，铁和锌的生物强化珍珠小米作为主要主食喂养2岁儿童时，铁和锌的吸收量足以满足这些微量营养素的生理需求。
Millet is unusually drought resistant and consequently there is a progressive increase in the use of these grains as a human food staple, especially in large areas of India and sub-Saharan Africa. The purpose of this study was to determine the absorption of iron and zinc from pearl millet biofortified with 2 micronutrients that are typically deficient in nonfortified, plant-based diets globally. The study was undertaken in 40 children aged 2 y in Karnataka, India (n = 21 test/19 controls). Three test meals providing ∼84 ± 17 g dry pearl millet flour were fed on a single day for zinc and 2 d for iron between 0900 and 1600 h. The quantities of zinc and iron absorbed were measured with established stable isotope extrinsic labeling techniques and analyses of duplicate diets. The mean (± SD) quantities of iron absorbed from test and control groups were 0.67 ± 0.48 and 0.23 ± 0.15 mg/d, respectively (P < 0.001). The quantities of zinc absorbed were 0.95 ± 0.47 and 0.67 ± 0.24 mg/d, respectively (P = 0.03). These data did not include absorption of the modest quantities of iron and zinc contained in snacks eaten before and after the 3 test meals. In conclusion, quantities of both iron and zinc absorbed when iron and zinc biofortified pearl millet is fed to children aged 2 y as the major food staple is more than adequate to meet the physiological requirements for these micronutrients.
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DOI：
10.1016/s0946-672x(99)80038-8
发表时间：
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影响因子：
3.5
作者：
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DOI：
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