Health related quality of life in coronary patients and its association with their cardiovascular risk profile: Results from the EUROASPIRE III survey
Health related quality of life in coronary patients and its association with their cardiovascular risk profile: Results from the EUROASPIRE III survey
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DOI：
10.1016/j.ijcard.2012.10.053
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发表时间：
2013-09-30
影响因子：
3.5
通讯作者：
De Bacquer, Dirk
中科院分区：
文献类型：
--
作者：
De Smedt, Delphine;Clays, Els;De Bacquer, Dirk
背景资料：心血管患者可能因功能和心理社会限制而导致健康相关生活质量（HRQoL）受损。本研究的主要目的是评估分布在22个欧洲国家的冠心病（CHD）患者的HRQoL评分，并确定与patients.Methods之间的变化相关的因素：数据从EUROASPIRE III调查（欧洲行动的二级和一级预防干预，以减少事件），对8734例患者，被使用。诊断为CHD（冠状动脉旁路移植术（CABG）、经皮冠状动脉介入治疗（PCI）、急性心肌梗死（AMI）或心肌缺血）的患者在急性冠状动脉事件发生后至少6个月接受采访和检查。使用2个标准化问卷测量每位患者的生活质量：EuroQoL-5D（EQ-5D）和12项简明健康调查表（SF-12 v2）。在女性、老年患者、受教育程度较低的患者、招募诊断为心肌梗死或缺血的患者、有卒中史的患者和患有复发性CHD事件的患者中发现HRQoL估计值较低。此外，HRQoL与糖尿病患者当前吸烟、向心性肥胖、缺乏运动和HbA 1c控制不当显著相关。此外，危险因素的数量与HRQoL.Conclusion呈负相关：总体而言，一个大的异质性观察到国家和患者组之间的HRQoL值。生活质量和患者特征之间似乎存在显著相关性，生活方式风险因素是HRQoL的重要决定因素。(c)2012爱思唯尔爱尔兰有限公司保留所有权利。
Background: Cardiovascular patients are likely to have an impaired health-related quality of life (HRQoL) due to functional and psycho-social limitations. The main objective of this study was to assess the distribution of HRQoL scores in coronary heart disease (CHD) patients across 22 European countries and to identify factors associated with the variation between patients.Methods: Data from the EUROASPIRE III survey (European Action on Secondary and Primary Prevention by Intervention to Reduce Events), on 8734 patients, were used. Patients with a diagnosis of CHD (coronary artery bypass graft (CABG), percutaneous coronary intervention (PCI), acute myocardial infarction (AMI) or myocardial ischemia) were interviewed and examined at least 6 months after their acute coronary event. Quality of life of each patient was measured using 2 standardized questionnaires: the EuroQoL-5D (EQ-5D) and the 12-item short-form health survey (SF-12v2).Results: HRQoL values differed significantly across countries. Lower HRQoL estimates were found in women, older patients, less educated patients, patients with myocardial infarction or ischemia as recruiting diagnosis, patients with a history of stroke and patients who suffered from a recurring CHD event. In addition, HRQoL was significantly associated with current smoking, central obesity, lack of exercise and inappropriate HbA1c control in patients with diabetes. Furthermore the number of risk factors is inversely associated with HRQoL.Conclusion: Overall, a large heterogeneity was observed in HRQoL values between countries and patient groups. There seems to be a significant association between quality of life and patient characteristics with lifestyle risk factors as important determinants of HRQoL. (c) 2012 Elsevier Ireland Ltd. All rights reserved.