Disorders of cerebral blood flow and intracranial pressure after head injury.
Disorders of cerebral blood flow and intracranial pressure after head injury.
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颅脑损伤后脑血流和颅内压紊乱。
DOI：
10.1093/neurosurgery/29.cn_suppl_1.162
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Miller,JD
中科院分区：
文献类型：
--
作者：
Miller,JD
颅脑损伤后的脑血流(CBF)和颅内压(ICP)紊乱是常见且重要的疾病。超过90%的死于头部损伤的患者患有缺血性脑损伤，通常位于大脑的多个区域(10)。在所有头部损伤死亡中，大约有一半(26例)，颅内压升高是脑死亡的主要原因。在重型颅脑损伤中，这两种形式的颅内疾病的潜在原因都很常见。这些症状包括肿块引起的脑变形、脑肿胀、脑灌注压降低、低氧血症和脑血管痉挛。在前一章中，已经概述了各种负责机制。本文研究了这些颅内疾病在实验性和人类颅脑损伤中的发生率，并评估了它们对颅脑损伤预后的意义。
Disorders of cerebral blood flow (CBF) and intracranial pressure (ICP) following head injury are both frequent and important. More than 90% of patients who die from head injury have ischaemic brain damage, usually in multiple areas of the brain (10). Increased ICP is the principal cause of brain death in approximately half of all head injury deaths (26). Potential causes for both forms of intracranial disturbance are rife in severe head injury. They include brain deformation by mass lesions, brain swelling, reduced cerebral perfusion pressure, hypoxemia, and cerebral vasospasm. In a previous chapter the various responsible mechanisms have been outlined. In this paper the incidence of these intracranial disorders in both experimental and human head injury is examined, and their significance for outcome from head injury is assessed.