Complement Receptor 1: disease associations and therapeutic implications.
Complement Receptor 1: disease associations and therapeutic implications.
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DOI:
10.1016/j.molimm.2008.09.026
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发表时间:
2009-03
影响因子:
3.6
通讯作者:
Das N
中科院分区:
文献类型:
--
作者:
Khera R;Das N
Exaggerated complement activation is a key event in the pathogenesis of a range of autoimmune and inflammatory diseases. Complement Receptor 1 (CR1) has emerged as a molecule of immense interest in gaining insight to the susceptibility, pathophysiology, diagnosis, prognosis and therapy of such diseases. This review brings forth a composite view of the current understanding on the structure, functions, genetics, disease associations and therapeutic implications of CR1.
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