Relation of blood-free to blood-inclusive postmortem lung water measurements in sheep.
Relation of blood-free to blood-inclusive postmortem lung water measurements in sheep.
复制标题
绵羊死后无血与含血肺水测量的关系。
DOI：
10.1152/jappl.1985.59.2.592
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Brigham,KL
中科院分区：
文献类型：
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作者：
Collins,JC;Newman,JH;Wickersham,NE;Vaughn,WK;Snapper,JR;Harris,TR;Brigham,KL
我们的目的是观察死后血管外肺水与无血干肺的重量比（无血比）是否与含血肺和血液中的类似比值相关。我们为73只绵羊在11种不同的方案下进行了研究，并为两个亚组的绵羊（一个有血浆空间扩张，另一个没有扩张）开发了无血率对含血肺和血液以及仅含血肺比率的线性回归。两组间无血肺与含血肺比值的关系不同。虽然所有回归都高度相关，但无血比率对含血肺和血液一起的比率的拟合优于仅含血肺。所有绵羊的血管外肺水的预测的平均误差为无血比回归血液和含血肺的比值（11 g）比仅含血肺（18 g）显着较小。这项研究表明，重量的肺匀浆和血液样品之前和之后的简单烘干可以用来提供准确的廉价估计死后血管外肺水。
Our purpose was to see if the postmortem weight ratio of extravascular lung water to blood-free dry lung (blood-free ratio) was related to similar ratios in blood-inclusive lung and in blood. We developed linear regressions of blood-free ratio on ratios for blood-inclusive lung and blood together and for blood-inclusive lung alone for 73 sheep studied under 11 different protocols and for two subgroups of sheep, one with plasma space expansion and the other without expansion. The relation of ratios of blood-free to blood-inclusive lungs was different between the two subgroups. Although all regressions were highly correlated, the fits of the blood-free ratio on ratios for blood-inclusive lung and blood together were better than for blood-inclusive lung alone. The mean error of prediction of extravascular lung water for all sheep was significantly less for the regression of blood-free ratio on ratios for blood and blood-inclusive lung together (11 g) than for blood-inclusive lung alone (18 g). This study shows that weights of lung homogenate and blood samples before and after simple oven drying can be used to provide accurate inexpensive estimates of postmortem extravascular lung water.