Act Healthy: A Randomized Clinical Trial Evaluating a Behavioral Activation Intervention to Address Substance Use and Medication Adherence Among Low-Income, Black/African American Individuals Living with HIV/AIDS.
Act Healthy: A Randomized Clinical Trial Evaluating a Behavioral Activation Intervention to Address Substance Use and Medication Adherence Among Low-Income, Black/African American Individuals Living with HIV/AIDS.
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DOI：
10.1007/s10461-021-03354-1
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发表时间：
2022-01
影响因子：
4.4
通讯作者：
Daughters SB
中科院分区：
文献类型：
--
作者：
Magidson JF;Belus JM;Seitz-Brown CJ;Tralka H;Safren SA;Daughters SB
有必要采取节俭的行为干预措施，以支持低收入、黑人/非裔美国人感染艾滋病毒的艾滋病毒和药物使用治疗结果。这项随机临床试验（N = 61）评估了Act health (AH)，一种减少药物使用和改善药物依从性的综合行为干预，与支持咨询（SC）加Life-Steps药物依从性咨询在药物使用、渴望、依从性相关结果和抑郁方面进行了一年的比较。与SC相比，AH组的参与者对物质的渴望明显下降，但在物质使用方面没有显著差异。在两组中，接受抗逆转录病毒治疗（ART）的概率显著增加（12个月时接受ART治疗的概率为86%，基线时为56%），药物依从性显著降低。研究结果为减少对抗逆转录病毒药物的渴望的干预措施和改善抗逆转录病毒药物使用的策略提供了初步支持，这些干预措施适用于难以接触到、治疗效果差和艾滋病毒传播风险高的弱势人群。
There is a need for parsimonious behavioral interventions to support HIV and substance use treatment outcomes for low-income, Black/African American individuals living with HIV. This randomized clinical trial (N = 61) evaluated Act Healthy (AH), an integrated behavioral intervention to reduce substance use and improve medication adherence, compared to supportive counseling (SC) plus Life-Steps medication adherence counseling on substance use, craving, adherence-related outcomes, and depression over one year. Participants in AH had significantly steeper decreases in cravings compared to SC, but no significant differences in substance use. Across both groups, there was a significant increase in probability of being on antiretroviral therapy (ART) (86% on ART at 12 months vs. 56% at baseline), and a significant decrease in medication nonadherence. Findings provide preliminary support for an intervention to reduce cravings and strategies to improve ART use in a hard-to-reach, vulnerable population at high risk for poor treatment outcomes and ongoing HIV transmission.
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影响因子：
3.9
作者：
Avants, SK;Margolin, A;Kosten, TR
通讯作者：
Kosten, TR
DOI：
10.1111/add.14049
发表时间：
2018-03
期刊：
Addiction (Abingdon, England)
影响因子：
--
作者：
Daughters SB;Magidson JF;Anand D;Seitz-Brown CJ;Chen Y;Baker S
通讯作者：
Baker S
影响因子：
2.9
作者：
Daughters SB;Magidson JF;Schuster RM;Safren SA
通讯作者：
Safren SA
影响因子：
3.9
作者：
Greenwood, GL;Woods, WJ;Bein, E
通讯作者：
Bein, E
影响因子：
9.7
作者：
Alegria, Margarita;Alvarez, Kiara;McPeck, Samantha
通讯作者：
McPeck, Samantha