Measurement of Liver Stiffness With Two Imaging Techniques: Magnetic Resonance Elastography and Ultrasound Elastometry
Measurement of Liver Stiffness With Two Imaging Techniques: Magnetic Resonance Elastography and Ultrasound Elastometry
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DOI：
10.1002/jmri.21523
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发表时间：
2008-11-01
影响因子：
4.4
通讯作者：
Tho, Marie-Christine Ho Ba
中科院分区：
文献类型：
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作者：
Bensamoun, Sabine F.;Wang, Lu;Tho, Marie-Christine Ho Ba
目的：为了交叉验证磁共振弹性成像（MRE）技术与临床设备，基于超声弹性测量系统称为Fibroscan.Materials和方法：10名健康受试者进行了MRE和Fibroscan测试。MRE技术使用60 Hz的圆形气动驱动器在肝脏内产生剪切波。生成表示肝脏硬度图的弹性图，允许测量感兴趣区域内的平均肝脏硬度。Fibroscan技术使用由振动器组成的超声探头（3.5 MHz），该振动器在右肝叶内发送低频（50 Hz）剪切波。探头作为一个发射器-接收器，测量的速度内传播的波的肝tissue.Results：平均剪切刚度测量与MRE和Fibroscan技术分别为1.95 +/- 0.06 kPa和1.79 +/- 0.30 kPa。一个更高的标准差被发现为同一主题与Fibroscan.Conclusion：这项研究表明，为什么MIRE应超越Fibroscan的调查。MRE技术提供了整个肝脏的弹性，而Fibroscan提供了局部的弹性值。
Purpose: To cross-validate the magnetic resonance elastography (MRE) technique with a clinical device, based on an ultrasound elastometry system called Fibroscan.Materials and Methods: Ten healthy subjects underwent an MRE and a Fibroscan test. The MRE technique used a round pneumatic driver at 60 Hz to generate shear waves inside the liver. An elastogram representing a map of the liver stiffness was generated allowing for the measurement of the average liver stiffness inside a region of interest. The Fibroscan technique used an ultrasound probe (3.5 MHz) composed of a vibrator that sent low-frequency (50 Hz) shear waves inside the right liver lobe. The probe acts as an emitter-receptor that measures the velocity of the waves propagated inside the liver tissue.Results: The mean shear stiffness measured with the MRE and Fibroscan techniques were 1.95 +/- 0.06 kPa and 1.79 +/- 0.30 kPa, respectively. A higher standard deviation was found for the same subject with Fibroscan.Conclusion: This study shows why MIRE should be investigated beyond the Fibroscan. The MRE technique provided elasticity of the entire liver, meanwhile the Fibroscan provided values of elasticity locally.