Normal performance on a simulated gambling task in treatment-naive alcohol-dependent individuals

Normal performance on a simulated gambling task in treatment-naive alcohol-dependent individuals
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DOI:
10.1111/j.1530-0277.2006.00109.x
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发表时间:
2006-06-01
影响因子:
3.2
通讯作者:
Finn, Peter
Finn, Peter
中科院分区:
医学3区
文献类型:
--
作者:
Fein, George;McGillivray, Shannon;Finn, Peter

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研究表明,物质滥用者在模拟赌博任务(SGT)上做出更不利的决定;这些决定与偏差倾向和反社会症状有关。本研究探讨了年轻成人酒精依赖谁是治疗初治(TxN)的SGT的决策。共有116名受试者(58名对照,58名TxN)进行了测试的SGT,其中参与者选择卡从4个不同的甲板上,不同的幅度的直接收益(大/小)和长期损失的幅度(大/小)。参与者还评估了外化症状的措施,反映社会偏差的人格特征,神经心理功能,和酒精中毒家族史的密度。模拟赌博任务的表现与外化症状,社会越轨倾向,或酗酒的家庭密度无关。虽然与对照组相比,TxN有更高水平的外化症状、社会偏差和酗酒的家庭密度,这些变量与先前长期戒酒的酒精依赖者样本相比仅略有升高,结果表明,我们的样本的年轻成人TxN成人酒精依赖没有全球赤字的决策所衡量的SGT,他们关于饮酒的糟糕决定更具体地说是饮酒。
Research suggests that substance abusers make more disadvantageous decisions on the simulated gambling task (SGT); such decisions are associated with deviance proneness and antisocial symptoms. This study examines decision making on the SGT in young adults with alcohol dependence who are treatment-naive (TxN).A total of 116 subjects (58 controls, 58 TxNs) were tested on the SGT, where participants choose cards from 4 different decks that vary in terms of the magnitude of the immediate gain (large/small) and the magnitude of long-term loss (larger/smaller). Participants were also assessed on measures of externalizing symptoms, personality traits reflecting social deviance, neuropsychological function, and the density of the family history of alcoholism.Treatment-naives did not differ from controls on measures of SGT decision making. Simulated gambling task performance was not associated with externalizing symptoms, social deviance proneness, or a familial density of alcoholism. Although TxNs had higher levels of externalizing symptoms, social deviance, and familial density of alcoholism compared with controls, these variables were only modestly elevated compared with previous samples of long-term abstinent alcohol-dependent individuals who showed decision-making deficits on the SGT.The results suggest that our sample of young adult TxN adults with alcohol dependence do not have global deficits in decision making as measured by the SGT, and that their poor decisions regarding their alcohol consumption are more specific to drinking.