Masked Hypertension Determined by Self-Measured Blood Pressure at Home and Chronic Kidney Disease in the Japanese General Population: The Ohasama Study
Masked Hypertension Determined by Self-Measured Blood Pressure at Home and Chronic Kidney Disease in the Japanese General Population: The Ohasama Study
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DOI：
10.1291/hypres.31.2129
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发表时间：
2008-12-01
影响因子：
5.4
通讯作者：
Imai, Yutaka
中科院分区：
文献类型：
--
作者：
Terawaki, Hiroyuki;Metoki, Hirohito;Imai, Yutaka
已知慢性肾脏疾病（CKD）和隐匿性高血压（MHT）均与心血管疾病（CVD）风险增加有关，但其关系尚不清楚。本研究旨在评价日本普通人群中MHT患者的CKD发病率。我们记录了1，365名个体的在家自测血压（HBP）和偶然血压（CBP）（平均63.0岁;男性，32.5%;平均肌酐清除率[CCr]，60.9 mL/min;阳性蛋白尿，6.7%），并将受试者分为四组：持续正常血压（SNBP，60.3%）、白大衣高血压（WCHT，14.9%）、MHT（12.8%）和持续高血压（SHT，12.0%）。各组的肾脏参数结果（SNBP，WCHT，MHT和SHT）如下：CCr分别为61.7、61.8、59.6、57.3 mL/min，蛋白尿阳性率分别为4.2%、8.9%、10.3%、12.8%，Ccr阳性率为9.8
Both chronic kidney disease (CKD) and masked hypertension (MHT) are known to be linked with an increased risk of cardiovascular disease (CVD), but their relationship has remained unclear. The present study aimed to evaluate the CKD incidence In Individuals with MHT in the general Japanese population. We recorded self-measured blood pressure at home (HBP) and casual blood pressure (CBP) In 1,365 individuals (mean 63.0 years old; males, 32.5%; mean creatinine clearance [CCr], 60.9 mL/min; positive proteinuria, 6.7%) and classified the subjects into four groups: sustained normal blood pressure (SNBP, 60.3%), white-coat hypertension (WCHT, 14.9%), MHT (12.8%), and sustained hypertension (SHT, 12.0%). Kidney parameter results for the respective groups (SNBP, WCHT, MHT, and SHT) were as follows: 61.7 mL/min, 61.8 mL/min, 59.6 mL/min, and 57.3 mL/min for CCr, 4.2%, 8.9%, 10.3%, and 12.8% for the prevalence of positive proteinuria, and 2.3%, 3.0%, 6.3%, and 9.8% for the proportion with CCr