EFFICACY AND APPLICABILITY OF MASS BCG VACCINATION IN TUBERCULOSIS CONTROL

EFFICACY AND APPLICABILITY OF MASS BCG VACCINATION IN TUBERCULOSIS CONTROL
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DOI:
10.1136/bmj.1.5540.587
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发表时间:
1967-01-01
影响因子:
--
通讯作者:
HART, PD
HART, PD
中科院分区:
医学1区
文献类型:
--
作者:
HART, PD

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马克·丹尼尔斯是他的密友。他是我在医学研究委员会结核病研究组工作了七年的同事。他在很大程度上负责了两项流行病学研究,为卡介苗接种的MRC试验铺平了道路--即这项研究的预测报告和全国结核病调查。1949年,当人们对卡介苗的价值存在很大分歧时,当时的MRC秘书爱德华·梅兰比爵士与格雷厄姆·威尔逊爵士、奥斯汀·布拉德福德·希尔爵士、庞顿·迪克博士、丹尼尔斯博士和我举行了一次会议,并由此成立了一个委员会,由我担任主席,以在英国对卡介苗的有效性进行试验。丹尼尔斯是该委员会的第一任秘书,并在试验开始期间和第一年的随访中担任协调人,直到1953年他去世。马克·丹尼尔斯在流行病学和统计学在结核病研究中的应用方面的兴趣是深远的。作为这项疫苗研究的构思、设计和开发的贡献者,他能够发挥自己的才华,产生巨大的效果。他将对结果及其影响感到着迷,我们可以肯定,这将有助于提高这一领域工作的质量和深度。这次演讲的主题非常恰当,是对马克·丹尼尔斯为医学所做贡献的致敬。
Marc Daniels was a close friend. He was my colleague for seven years on the Medical Research Council's Tuberculosis Research Unit. He was largely responsible for two epidemiological researches paving the way to the MRC trial of BCG vaccination-namely, the ProphitReport of thisCollege on Tuberculosis in Young Adults, and the National Tuberculin Survey. In 1949, when there was much disagreement on the value of BCG, Sir Edward Mellanby, then Secretary of the MRC, held a conference with Sir Graham Wilson, Sir Austin Bradford Hill, Dr. Pointon Dick, Daniels, and me, and arising from this a committee was formed, with myself as chairman, to conduct a trial on the efficacy of BCG in Britain. Daniels was its first secretary, and was co-ordinator of the trial during its intake and for the first year of its follow-up until his death in 1953.Marc Daniels's interests in epidemiology and in the applica-tion of statistics in tuberculosis research were far-reaching. As a contributor to the conception, design, and development of this vaccines study he was able to bring his talents to bear with great effect. He would have been fascinated by the results and their implications, and would, we may be sure, have helped to improve the quality and depth of work in this field. The subject of this lecture is highly appropriate as a tribute to the services of Marc Daniels to medicine.