Scientific misconduct from the perspective of research coordinators: a national survey
Scientific misconduct from the perspective of research coordinators: a national survey
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DOI：
10.1136/jme.2006.016394
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发表时间：
2007-06-01
影响因子：
4.1
通讯作者：
Broome, Marion E.
中科院分区：
文献类型：
--
作者：
Pryor, Erica R.;Habermann, Barbara;Broome, Marion E.
目的：报告对美国临床研究协调员和管理者进行的一项全国调查结果，了解他们对科学不端行为的看法和经历。方法：使用科学不端行为问卷修订版收集数据。 2004 年 2 月至 2005 年 1 月期间，向临床研究专业人员协会成员和临床研究实践中心出版的《研究从业者》订阅者发送了 5302 份调查，其中 1645 份（31%）收到了符合条件的答复。调查结果：总体而言，感知到的不当行为频率较低。在调查人员和研究协调员所感受到的压力以及监管环境在减少不当行为方面的有效性方面，工作场所之间存在差异。 18% 的受访者报告了不当行为事件的第一手经历。那些对不当行为有第一手了解的人更有可能报告在学术医疗环境中工作，并报告说，如果意识到主要研究者或研究人员卷入不当行为事件，典型的研究协调员可能不会采取任何行动。结论：这些发现通过从研究协调员的角度添加新信息，扩展了对科学不当行为的认识。研究结果提供了一些数据，支持工作场所氛围对不当行为的影响，以及减少科学不当行为的机构政策的有效性。
Objective: To report results from a national survey of coordinators and managers of clinical research studies in the US on their perceptions of and experiences with scientific misconduct.Methods: Data were collected using the Scientific Misconduct Questionnaire-Revised. Eligible responses were received from 1645 of 5302 (31%) surveys sent to members of the Association of Clinical Research Professionals and to subscribers of Research Practitioner, published by the Center for Clinical Research Practice, between February 2004 and January 2005.Findings: Overall, the perceived frequency of misconduct was low. Differences were noted between workplaces with regard to perceived pressures on investigators and research coordinators, and on the effectiveness of the regulatory environment in reducing misconduct. First-hand experience with an incident of misconduct was reported by 18% of respondents. Those with first-hand knowledge of misconduct were more likely to report working in an academic medical setting, and to report that a typical research coordinator would probably do nothing if aware that a principal investigator or research staff member was involved in an incident of misconduct.Conclusion: These findings expand the knowledge on scientific misconduct by adding new information from the perspective of research coordinators. The findings provide some data supporting the influence of workplace climate on misconduct and also on the perceived effectiveness of institutional policies to reduce scientific misconduct.