Assessment of sex-specific differences in adverse events following immunization reporting in Ontario, 2012-15

Assessment of sex-specific differences in adverse events following immunization reporting in Ontario, 2012-15
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DOI:
10.1016/j.vaccine.2017.03.035
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发表时间:
2017-05-02
期刊:
影响因子:
5.5
通讯作者:
Deeks, Shelley L.
Deeks, Shelley L.
中科院分区:
医学3区
文献类型:
--
作者:
Harris, Tara;Nair, Jyotsna;Deeks, Shelley L.

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我们评估了加拿大安大略被动疫苗安全性监测中的性别特异性趋势。包括2012年至2015年期间接种疫苗后报告的AEFI。共有2466份AARNIA报告; 66.2%为女性。女性和男性的年度报告率分别为每100 000人5.9和3.1。女性:男性报告率比(RRR)为1.9。不同年龄组的性别差异在18-64岁的成年人中最大(RRR6.3);而在儿童中没有差异
We assessed sex-specific trends within passive vaccine safety surveillance in Ontario, Canada. AEFIs reported following vaccines administered between 2012 and 2015 were included. There were 2466 AEFI reports; 66.2% were female. Annualized reporting rates were 5.9 and 3.1 per 100,000 population, for females and males respectively. The female:male reporting rate ratio (RRR) was 1.9. Sex-specific differences by age group were greatest in adults 18-64 years (RRR 6.3); whereas there were no differences in children