Decrease in jugular venous oxygen saturation during normothermic cardiopulmonary bypass predicts short-term postoperative neurologic dysfunction in elderly patients

Decrease in jugular venous oxygen saturation during normothermic cardiopulmonary bypass predicts short-term postoperative neurologic dysfunction in elderly patients
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DOI:
10.1016/s0735-1097(01)01584-4
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发表时间:
2001-11-01
影响因子:
24
通讯作者:
Fujita, N
Fujita, N
中科院分区:
医学1区
文献类型:
--
作者:
Kadoi, Y;Saito, S;Fujita, N

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我们试图检验在心肺转流(CPB)期间颈静脉血氧饱和度(Sjvo(2))的降低是否可以用来预测老年患者术后短期和长期的认知障碍。研究了第1组(n = 56)为年轻(70岁)。麻醉诱导后,将光纤血氧饱和度导管插入右颈静脉球,连续监测Sjvo(2)。在7个时间点测定血流动力学参数和动脉及颈静脉血气。
OBJECTIVES We sought to examine whether the decrease in jugular venous oxygen saturation (Sjvo(2)) during cardiopulmonary bypass (CPB) can be used to predict short-term and long-term postoperative cognitive disorders in elderly patients.BACKGROUND It has been reported that elderly patients might be more susceptible to hypoperfusion during CPB.METHODS One hundred eighty-five patients scheduled for elective coronary artery bypass graft surgery, were studied. Group 1 (n = 56) was young (70 years old). After induction of anesthesia, a fiberoptic oximetry oxygen saturation catheter was inserted into the right jugular bulb to monitor Sjvo(2) continuously. Hemodynamic variables and arterial and jugular venous blood gases were measured at seven time points.RESULTS The cerebral desaturation time (duration when Sjvo(2) was