The photoreceptor mosaic
The photoreceptor mosaic
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DOI：
10.1038/eye.1998.142
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发表时间：
1998-06-01
期刊：
影响因子：
3.9
通讯作者：
Ahnelt, PK
中科院分区：
文献类型：
--
作者：
Ahnelt, PK
人类光感受器马赛克的组织反映了在广泛的刺激条件下优化视觉信息的进化策略：（1）视杆细胞占主导地位（最大。170 000/mm（2），c. 30 degrees sup.）除了中央2度和沿着锯齿缘。(2)中心凹内锥体内/外节密度达300 000 mm（2）。一捆C。300-500个小窝锥体通过其突触末端位于无毛细血管区内而进一步区分。中心凹周围激光治疗可使中心凹色调终末径向移位（>350 μ m），导致两组视锥通路病变。沿着锯齿缘周边锥体密度（c. 4000）在一个小的边缘（1度）内上升到20000，但可能会因囊样变性而显著降低。对于L-和M-锥亚群的比例为2：1至1：1和随机安排的建议。(3)蓝敏感（S-）锥构成了一个规则的和独立的亚马赛克的c。7%的外围。在c处的环形最大值（1000-5000/mm（2））。10围绕着小凹。那里密度降低，缺乏S-锥的不规则区域导致tritan缺乏。
The organisation of the human photoreceptor mosaic reflects evolutionary strategies for optimising visual information under a wide range of stimulus conditions: (1) The rod population dominates (max. 170 000/mm(2) at c. 30 degrees sup.) except for the central 2 degrees and along the ora serrata. (2) Density of cone inner/outer segments reaches up to 300 000 mm(2) in the fovea. A bundle of c. 300-500 foveolar cones are further distinguished by having their synaptic terminals located within the capillary-free zone. Radial displacement (>350 mu m) of foveal tone terminals may result in the lesion of two sets of cone pathways by perifoveal laser treatment. Along the ora serrata peripheral cone density (c. 4000) rises within a small rim (1 degrees) to up to 20 000, but may be considerably decreased by cystoid degenerations. For the L- and M-cone subpopulations ratios of 2:1 to 1:1 and random arrangement are suggested. (3) Blue-sensitive (S-) cones constitute a regular and independent submosaic of c. 7% across the periphery. An annular maximum (1000-5000/mm(2)) at c. 10 surrounds the foveola. There density decreases and irregular zones lacking S-cones result in tritan deficiencies.