Macrophage migration inhibitory factor: A probable link between inflammation and cancer

Macrophage migration inhibitory factor: A probable link between inflammation and cancer
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DOI:
10.1016/j.immuni.2007.03.005
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发表时间:
2007-03-01
期刊:
影响因子:
32.4
通讯作者:
Donnelly, Seamas C.
Donnelly, Seamas C.
中科院分区:
医学1区
文献类型:
--
作者:
Bucala, Richard;Donnelly, Seamas C.

文献摘要

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巨噬细胞迁移抑制因子(MIF)的多种作用使其在许多疾病的免疫发病机制中处于中心地位。在这里,我们讨论了目前对MIF作用的理解,并强调它是炎症激活和恶性进展之间的潜在联系。
hThe pleiotropic effects of macrophage migration inhibitory factor (MIF) place it in a central position in the immunopathogenesis of many diseases. Here we discuss the current understanding of MIF's role and highlight it as a potential link between inflammatory activation and malignant progression.