Tissue analysis using optical and mechanical tissue properties obtained by polarization-sensitive optical coherence elastography
Tissue analysis using optical and mechanical tissue properties obtained by polarization-sensitive optical coherence elastography
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使用通过偏振敏感光学相干弹性成像获得的光学和机械组织特性进行组织分析
DOI：
10.1117/12.2544687
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Yasuno Yoshiaki
中科院分区：
文献类型：
--
作者：
Miyazawa Arata;Makita Shuichi;Li En;Yamazaki Kohei;Kobayashi Masaki;Sakai Shingo;Yasuno Yoshiaki
发展了偏振敏感光学相干弹性成像技术。它将基于琼斯矩阵的偏振敏感光学相干层析成像与压缩OCE相结合。该方法同时测量OCT、衰减系数、双折射和组织机械特性。用PS-OCE法测定体外猪的食道。热致变性使薄膜的衰减系数、双折射、面内横向位移和微结构变形等光学和力学性能都发生了明显的变化。
Polarization-sensitive optical coherence elastography was developed. It integrates Jones matrix-based polarization-sensitive optical coherence tomography with compression OCE. The method simultaneously measures OCT, attenuation coefficient, birefringence, and tissue mechanical properties. Ex-vivo porcine esophagus was measured by PS-OCE. Evident alteration caused by heat-induced denaturation was obtained in almost all of the optical and mechanical properties including attenuation coefficient, birefringence, in-plane lateral displacement, and microstructural deformation.