Principles Underlying New Methods for Chronic Neural Recording
Principles Underlying New Methods for Chronic Neural Recording
复制标题
慢性神经记录新方法的原理
DOI：
10.1017/s0317167100020333
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发表时间：
1975
期刊：
影响因子：
--
通讯作者：
T. R. Nichols
中科院分区：
文献类型：
--
作者：
Richard B. Stein;D. Charles;L. Davis;Jack H. Jhamandas;A. Mannard;T. R. Nichols
摘要：通过绝缘介质中的孔生长的神经纤维(再生电极)或被绝缘鞘包裹的神经纤维(袖带电极)可以进行慢性记录。在平衡配置中使用三个电极可以很好地抑制肌电(EMG)信号和其他电子干扰源(荧光灯、来自电源的60赫兹信号等)。推导并测试了在给定的袖带长度和直径下，预测信号的幅度和形状的方程。这些方程可以用来为给定的应用优化设计电极单元。最后，使用变压器可以使神经信号与记录设备仔细匹配，并进一步优化神经信号与噪声和信号与肌电的比率。这些方法的使用在几个生理和临床应用，以及潜在的滥用，进行了讨论。
SUMMARY: Chronic recording is possible from nerve fibers which have grown through holes in an insulating medium (regeneration electrodes) or which are enclosed by an insulating sheath (cuff electrodes). Use of three electrodes in a balanced configuration permits good rejection of electromyographic (EMG) signals and other sources of electrical interference (fluorescent lights, 60 Hz signals from the mains, etc.). Equations are derived and tested for predicting the amplitude and form of the signals expected for a given cuff length and diameter. These equations can be used to design electrode units optimally for a given application. Finally, the use of transformers permits the neural signals to be carefully matched to the recording apparatus and further optimizes the neural signal-to-noise and signal-to-EMG ratios. Use of these methods in several physiological and clinical applications, as well as potential abuses, are discussed.