Agreement between patient interview data on prescription medication use and pharmacy records in those aged older than 50 years varied by therapeutic group and reporting of indicated health conditions
Agreement between patient interview data on prescription medication use and pharmacy records in those aged older than 50 years varied by therapeutic group and reporting of indicated health conditions
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DOI：
10.1016/j.jclinepi.2013.02.016
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发表时间：
2013-11-01
影响因子：
7.2
通讯作者：
Bennett, Kathleen
中科院分区：
文献类型：
--
作者：
Richardson, Kathryn;Kenny, Rose Anne;Bennett, Kathleen
目的：为了估计之间的协议，访谈确定的药物使用和药房记录的人口年龄超过50岁，并确定患者水平的预测discordance.Study设计和设置：爱尔兰的纵向研究老龄化是代表社区居住的成年人年龄在50岁及以上的爱尔兰。来自2，621名参与者的采访确定的药物数据与药房配药记录相关联。Kappa统计量测量了19个治疗类别的两个来源之间的一致性。Logistic回归分析评估了患者水平特征对定期分发药物的低报和高报调查的影响。一致性良好或非常好（kappa = 0.64-0.86），抗风湿药和抗风湿药的疗效为中等或较差（kappa = 0.54）、镇痛剂（kappa = 0.50）、精神抑制剂（kappa = 0.59）和眼科药物（kappa = 0.37）。未报告指示的健康状况，不频繁的配药，年龄较大，更多的药物定期分发与调查报告不足，但结果不同的治疗类。记忆和认知与discordance.Conclusion：通过患者访谈确定药物使用似乎是一种有效的方法，大多数药物类，也捕捉非处方药和补充剂的使用。然而，局部用药和按需用药可能会少报。在进行药物流行病学研究时，应仔细考虑用药数据的来源。(c)2013 Elsevier Inc. All rights reserved.
Objectives: To estimate the agreement between interview-ascertained medication use and pharmacy records among the population aged older than 50 years, and to identify patient-level predictors of discordance.Study Design and Setting: The Irish Longitudinal study on Ageing is representative of community-dwelling adults aged 50 years and older in Ireland. Interview-ascertained medication data from 2,621 participants were linked to pharmacy dispensing records. The kappa statistics measured the agreement between the two sources for 19 therapeutic classes. Logistic regression assessed the effect of patient-level characteristics on survey under- and overreporting of regularly dispensed medications.Results: Agreement was good or very good (kappa = 0.64-0.86) for 15 medication classes, and moderate or poor for antiinflammatory and antirheumatic products (kappa = 0.54), analgesics (kappa = 0.50), psycholeptics (kappa = 0.59), and ophthalmologicals (kappa = 0.37). Not reporting an indicated health condition, less frequent dispensing, older age, and more medications regularly dispensed were associated with survey under-reporting, but results varied by therapeutic class. Memory and cognition were not associated with discordance.Conclusion: Ascertaining medication use via patient interview seems a valid method for most medication classes and also captures nonprescription and supplement use. However, medications applied topically and as needed may be underreported. The source of medication data should be carefully considered when performing pharmacoepidemiological studies. (c) 2013 Elsevier Inc. All rights reserved.