The Impact of Obesity in Heart Failure
The Impact of Obesity in Heart Failure
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DOI：
10.1016/j.hfc.2019.08.008
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发表时间：
2020-01-01
影响因子：
3.4
通讯作者：
Ventura, Hector O.
中科院分区：
文献类型：
--
作者：
Carbone, Salvatore;Lavie, Carl J.;Ventura, Hector O.
超重和肥胖对心脏结构和功能产生不利影响，影响收缩和舒张心室功能。流行病学研究已经证明了大型心力衰竭队列中的肥胖悖论，与较瘦的患者相比，超重和肥胖的心力衰竭患者具有更好的短期和中期预后;这种关系受到心肺适应性水平的强烈影响。对于旨在增加瘦体重以及减轻体重和改善饮食质量的治疗，对于预防和治疗心力衰竭和伴随的肥胖症以改善心肺适应性具有意义。
Overweight and obesity adversely impact cardiac structure and function, affecting systolic and diastolic ventricular function. Epidemiologic studies have documented an obesity paradox in large heart failure cohorts, where overweight and obese individuals with established heart failure have a better short- and medium-term prognosis compared with leaner patients; this relationship is strongly impacted by level of cardiorespiratory fitness. There are implications for therapies aimed at increasing lean mass as well as weight loss and improvements in quality of diet for the prevention and treatment of heart failure and concomitant obesity to improve cardiorespiratory fitness.