Direct Preparation of Heteroaromatic Compounds from Alkenes
Direct Preparation of Heteroaromatic Compounds from Alkenes
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DOI：
10.1055/s-0030-1259034
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发表时间：
2010-12-01
期刊：
影响因子：
2
通讯作者：
Smith, Ian E. D.
中科院分区：
文献类型：
--
作者：
Donohoe, Timothy J.;Kabeshov, Mikhail A.;Smith, Ian E. D.
一系列芳香杂环，噻唑，咪唑和二甲氧基吲哚，可以通过酮碘环化方案直接由烯烃合成。烯烃起始原料本身很容易通过许多不同的和成熟的方法获得，并且可以获得各种芳香杂环，具有优异的收率和区域选择性。
A series of aromatic heterocycles, thiazoles, imidazoles, and dimethoxyindoles, can be synthesised directly from alkenes via a ketoiodination-cyclisation protocol. The alkene starting materials are themselves easily accessible by many different and well-established approaches, and allow access to various aromatic heterocycles with excellent yields and regioselectivity.