Relationship between physical activity and intramyocellular lipid content is different between young and older adults

Relationship between physical activity and intramyocellular lipid content is different between young and older adults
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DOI:
10.1007/s00421-018-4005-x
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发表时间:
2019-01-01
影响因子:
3
通讯作者:
Akima, Hiroshi
Akima, Hiroshi
中科院分区:
医学3区
文献类型:
--
作者:
Hioki, Maya;Kanehira, Nana;Akima, Hiroshi

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目的体育锻炼对细胞内脂质(IMCL)的影响;然而,习惯性的体育活动水平是否会影响静息期IMCL含量仍不清楚。本研究的目的是确定年轻人和老年人体力活动水平与静息IMCL含量之间的关系。方法共招募15名非肥胖青年(21.00.0岁)和15名老年人(70.73.8岁)。使用三维动态加速度计评估10天内进行体力活动的时间,强度分类为轻度[6.0 METs]。体力活动水平计算为METs和在每个强度水平上进行体力活动(METh)所花费的时间的乘积。禁食过夜后用h -1磁共振波谱法测定股外侧肌IMCL含量。结果青壮年和老年人血清IMCL含量无显著性差异。高强度体力活动(时间和冰毒)在老年人中显著低于年轻人(p
PurposeIntramyocellular lipid (IMCL) is influenced by physical exercise; however, whether the habitual level of physical activity affects resting IMCL content remains unclear. The purpose of this study was to determine the relationship between physical activity levels and resting IMCL content in young and older adults.MethodsIn total, 15 nonobese young adults (21.00.0years) and 15 older adults (70.73.8years) were recruited. Time spent performing physical activities for 10days was assessed using a three-dimensional ambulatory accelerometer, and intensity was categorized as light [6.0 METs). Physical activity level was calculated as the product of METs and time spent performing physical activities (METh) at each intensity level. The IMCL content in the vastus lateralis was determined using H-1-magnetic resonance spectroscopy after overnight fasting.ResultsNo significant differences in IMCL content were observed between young and older adults. Vigorous intensity physical activity (time and METh) was significantly lower in older than young adults (p