Optically Triggered Melting of DNA on Individual Semiconducting Carbon Nanotubes.
Optically Triggered Melting of DNA on Individual Semiconducting Carbon Nanotubes.
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DOI：
10.1002/anie.201703332
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发表时间：
2017-08-01
期刊：
影响因子：
--
通讯作者：
Wang Y
中科院分区：
文献类型：
--
作者：
Wang C;Meany B;Wang Y
已知纳米结构的光激发会引起局部加热，这种现象已被广泛用于药物释放、基因递送、癌症热疗和能量收集。然而，该效果通常很小，需要集体加热大浓度或聚集的颗粒。在这里，我们表明，单个半导体单壁碳纳米管的光激发触发强烈的局部加热足以熔化溶液中的非共价连接的双链寡核苷酸。与传统的热去杂交相反，这种光学触发的DNA解链发生在比DNA解链温度低22 ° C的溶液温度下。这种出乎意料的大的局部光学加热效应提供了重要的新见解，设计选择性的光学纳米加热器在单粒子水平。
Optical excitation of nanostructures is known to induce local heating, a phenomenon that has been intensely exploited for drug release, gene delivery, cancer thermotherapy, and energy harvesting. However, the effect is typically small requiring collective heating of a large concentration or aggregates of particles. Here we show that optical excitation of individual semiconducting single-walled carbon nanotubes triggers strongly localized heating adequate to melt non-covalently attached double-stranded oligonucleotides in solution. In contrast to conventional thermal dehybridization, this optically triggered DNA melting occurs at a solution temperature that is 22 °C lower than the DNA melting temperature. This unexpectedly large localized optical heating effect provides important new insights to design selective optical nanoheaters at the single particle level.
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影响因子：
15
作者：
Huschka, Ryan;Zuloaga, Jorge;Knight, Mark W.;Brown, Lisa V.;Nordlander, Peter;Halas, Naomi J.
通讯作者：
Halas, Naomi J.
DOI：
10.1073/pnas.2232479100
发表时间：
2003-11-11
影响因子：
11.1
作者：
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通讯作者：
West, JL
影响因子：
15
作者：
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通讯作者：
Hertel, Tobias
影响因子：
15
作者：
Ming, Z;Diner, BA
通讯作者：
Diner, BA
影响因子：
3.3
作者：
Jain, PK;Lee, KS;El-Sayed, MA
通讯作者：
El-Sayed, MA