Age-related odontometric changes of human teeth
Age-related odontometric changes of human teeth
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DOI：
10.1067/moe.2002.120974
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发表时间：
2002-04-01
影响因子：
--
通讯作者：
Smith, AJ
中科院分区：
文献类型：
--
作者：
Murray, PE;Stanley, HR;Smith, AJ
Objective.由于口腔健康的改善和寿命的延长，需要恢复性治疗的老年患者数量可能会增加。然而，缺乏老化的牙齿测量数据。本研究的目的是确定牙髓细胞密度、牙髓面积和牙本质厚度随年龄的可能变化。对60例年龄在10 ~ 59岁之间的患者的切牙（50例）、尖牙（39例）、前磨牙（51例）和磨牙（7例）的细胞密度（成牙本质细胞、亚成牙本质细胞和髓芯成纤维细胞）和牙本质厚度进行组织形态计量学分析。随着患者年龄的增长，在牙冠和牙根方面，牙本质厚度增加（P < .001），而成牙本质细胞（P <.001），成牙本质细胞（P = 0.001）和牙髓成纤维细胞（牙冠，P < .011;牙根，P = .0015）的密度下降。与年龄相关的牙齿变化的程度似乎是不对称的，在根减少大于冠。在所有年龄组中，尽管计算出的牙本质沉积率在牙根中最高，但牙冠中的牙髓细胞密度（包括成牙本质细胞）均高于牙根（P <0.001）。牙髓细胞密度的降低可能会降低修复治疗后的牙髓修复活性，尽管牙本质厚度的增加可能有助于牙髓保护。了解这些与年龄有关的变化将影响修复和根管治疗的提供，并使老年患者受益。
Objective. The number of older patients requiring restorative treatment are likely to increase due to improvements in oral health and increased longevity. However, aging odontometric data are lacking. The aim of this study was to determine possible changes in pulp cell density, pulp area, and dentinal thickness with age.Study design. Incisors (50), canines (39), premolars (51), and molars (7) extracted from 60 patients aged between 10 and 59 years, were analyzed histomorphometrically for cell density (odontoblasts, subodontoblasts, and pulp core fibroblasts) and dentinal thickness.Results. With increasing patient age, in both crown and root aspects of teeth, dentinal thickness increased (P < .001), while the density of odontoblasts (P < .001), subodontoblasts (P = 0.001), and pulp fibroblasts (crown, P < .011; root, P = .0015) decreased. The degree of age-related changes in teeth appeared to be asymmetrical, with decreases in the root being greater than in the crown. At all ages pulp cell densities, including odontoblasts, within the crown were greater than in the root (P < .001), even though the calculated rate of dentinal deposition was greatest in the root.Conclusion. Decreases in pulp cell density may reduce pulp repair activity after restorative treatments, although increases in dentinal thickness may aid pulp protection. An understanding of these age-related changes will influence the provision of restorative and endodontic care and benefit older patients.