Selective decontamination of the digestive tract reduces mortality in critically ill patients.
Selective decontamination of the digestive tract reduces mortality in critically ill patients.
复制标题
消化道的选择性净化可降低危重患者的死亡率。
DOI:
10.1186/cc1873
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发表时间:
2003-04
期刊:
影响因子:
15.1
通讯作者:
Kesecioglu, J
中科院分区:
文献类型:
--
作者:
Schultz, MJ;de Jonge, E;Kesecioglu, J
Several emotional responses may be invoked in critical care physicians when confronted with selective decontamination of the digestive tract (SDD). Although recent meta-analyses have shown that the use of SDD reduces the occurrence of ventilator-associated pneumonia and improves ICU survival, the effectiveness of SDD has remained controversial. We recently concluded a large randomized, controlled trial on the use of SDD that showed improved survival of ICU patients treated with SDD. A second concern regarding use of SDD has been the fear for the emergence of antimicrobial resistance. Interestingly, a recently published study did not confirm this fear, and our recently finished study even demonstrated a decline in colonization with P. aeruginosa and enterobacteriaceae that were resistant against tobramycin, ceftazidime, imipenem and ciprofloxacin. The hopes are that this study will at long last end the debate about the efficacy and safety of SDD in critically ill patients.
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影响因子:
39.2
作者:
COCKERILL, FR;MULLER, SR;THOMPSON, RL
通讯作者:
THOMPSON, RL
影响因子:
38.9
作者:
ROCHA, LA;MARTIN, MJ;DURAN, MT
通讯作者:
DURAN, MT
影响因子:
6.9
作者:
Lingnau, W;Berger, J;Benzer, H
通讯作者:
Benzer, H
影响因子:
8.8
作者:
KERVER, AJH;ROMMES, JH;WITTEBOL, P
通讯作者:
WITTEBOL, P
DOI:
10.1164/rccm.2105141
发表时间:
2002-10-15
影响因子:
24.7
作者:
Krueger, WA;Lenhart, FP;Unertl, KE
通讯作者:
Unertl, KE