Fine needle aspiration cytology of metastatic malignant schwannoma. A case report.
Fine needle aspiration cytology of metastatic malignant schwannoma. A case report.
复制标题
转移性恶性神经鞘瘤的细针抽吸细胞学检查。
作者：
Schwartz Jg;Dowd Dc
据报道，一名 56 岁男性经细针抽吸 (FNA) 活检诊断出转移性恶性神经鞘瘤。对从椎体肿块抽吸物中制备的涂片和细胞块进行的细胞学检查表明，右腿上存在先前切除的恶性神经鞘瘤的转移。对抽吸物进行的电子显微镜和免疫细胞化学研究支持了诊断，患者的临床病史和既往病理以及肺部转移性病变的放射学证明也支持了诊断。根据该病变的组织学多样性以及将其与其他肉瘤区分开来的问题，讨论了细胞学发现（具有椭圆形至纺锤形细胞核和不明确的细胞边界的细胞悬浮在精致的纤维状嗜酸性基质中）。通过 FNA 诊断转移性恶性神经鞘瘤的能力强调了该技术的价值。
A metastatic malignant schwannoma diagnosed by fine needle aspiration (FNA) biopsy in a 56-year-old man is reported. Cytologic examination of smears and cell blocks prepared from aspirates of a vertebral mass suggested the presence of metastases from a previously excised malignant schwannoma on the right leg. Electron microscopic and immunocytochemical studies on the aspirate supported the diagnosis, as did the patient's clinical history and previous pathology and the radiographic demonstration of metastatic lesions in the lung. The cytologic findings (cells with oval-to-spindled nuclei and ill-defined cellular borders suspended within a delicately fibrillar eosinophilic matrix) are discussed in light of the histologic diversity of this lesion and the problems of distinguishing it from other sarcomas. The ability to diagnose metastatic malignant schwannoma by FNA emphasizes the value of this technique.