Mitochondrial functions in plant immunity
Mitochondrial functions in plant immunity
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线粒体在植物免疫中的功能
DOI：
10.1016/j.tplants.2022.04.007
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发表时间：
2022
影响因子：
20.5
通讯作者：
Wang Guo-Liang
中科院分区：
文献类型：
--
作者：
Wang Jiyang;Xu Guojuan;Ning Yuese;Wang Xuli;Wang Guo-Liang
线粒体是细胞的能量工厂，对于细胞内与其他细胞器的相互作用非常重要。新出现的证据表明，线粒体在病原体感染的反应中发挥重要作用。在感染期间，病原体将许多酶和效应物递送到宿主细胞中，并且这些效应物中的一些靶向线粒体，改变线粒体形态、代谢和功能。为了抵御病原体的攻击，线粒体积极参与改变细胞内代谢、线粒体介导的信号传导和信号转导，产生活性氧和活性氮并触发程序性细胞死亡。此外，线粒体与其他细胞器协调，以整合和放大各种免疫信号。在这篇综述中，我们总结了最近的进展，了解线粒体在植物免疫中的功能，以及病原体如何靶向线粒体宿主防御抑制。
Mitochondria are energy factories of cells and are important for intracellular interactions with other organelles. Emerging evidence indicates that mitochondria play essential roles in the response to pathogen infection. During infection, pathogens deliver numerous enzymes and effectors into host cells, and some of these effectors target mitochondria, altering mitochondrial morphology, metabolism, and functions. To defend against pathogen attack, mitochondria are actively involved in changing intracellular metabolism, hormone-mediated signaling, and signal transduction, producing reactive oxygen species and reactive nitrogen species and triggering programmed cell death. Additionally, mitochondria coordinate with other organelles to integrate and amplify diverse immune signals. In this review, we summarize recent advances in understanding how mitochondria function in plant immunity and how pathogens target mitochondria for host defense suppression.