Cylindrical polymer brushes - Anisotropic building blocks, unimolecular templates and particulate nanocarriers
Cylindrical polymer brushes - Anisotropic building blocks, unimolecular templates and particulate nanocarriers
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DOI：
10.1016/j.polymer.2016.03.076
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发表时间：
2016-08-19
期刊：
影响因子：
4.6
通讯作者：
Mueller, Axel H. E.
中科院分区：
文献类型：
--
作者：
Muellner, Markus;Mueller, Axel H. E.
本文介绍了圆柱形聚合物刷（CPB），也被称为“分子瓶刷”领域的最新关键进展和研究活动的概述。CPB由含有聚合物侧链的聚合物主链组成，所述聚合物侧链导致主链延伸并采用蠕虫状构象。侧链的长度和接枝密度决定了CPB的主链拉伸程度和纵横比。受控/活性聚合技术的最新发展导致了生产精细聚合物结构（例如嵌段共聚物CPB）的新颖且更有效的方法，并导致这些软各向异性材料的应用领域的相当大的扩展。在这篇专题文章中，我们专注于最近的重要发现和应用领域有关的解决方案和散装自组装嵌段共聚物CPB，单分子模板和刷为基础的药物输送系统在纳米医学。(C)2016爱思唯尔有限公司版权所有
This article presents an overview of the latest key developments and research activities in the area of cylindrical polymer brushes (CPBs), also known as 'molecular bottlebrushes'. CPBs consist of a polymer backbone containing polymer side chains that cause the backbone to extend and adopt a worm-like conformation. The extent of backbone stretching and the aspect ratio of CPBs is determined by the length and grafting density of the side chains. The latest developments in controlled/living polymerisation techniques led to novel and more efficient ways of producing delicate polymer architectures, such as block copolymer CPBs, and resulted in a considerable expansion of the field of application for these soft anisotropic materials. In this feature article, we focus on important recent findings and applications in the areas concerning solution and bulk self-assembly of block copolymer CPBs, unimolecular templating and brush-based drug delivery systems in nanomedicine. (C) 2016 Elsevier Ltd. All rights reserved.