A COMPUTER-PROGRAM IN COMPILED BASIC FOR THE IBM PERSONAL-COMPUTER TO CALCULATE THE MEAN PLATELET SURVIVAL-TIME WITH THE MULTIPLE-HIT AND WEIGHTED MEAN METHODS
A COMPUTER-PROGRAM IN COMPILED BASIC FOR THE IBM PERSONAL-COMPUTER TO CALCULATE THE MEAN PLATELET SURVIVAL-TIME WITH THE MULTIPLE-HIT AND WEIGHTED MEAN METHODS
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DOI：
10.1016/0010-4825(88)90006-6
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发表时间：
1988-01-01
影响因子：
7.7
通讯作者：
MINNAAR, PC
中科院分区：
文献类型：
--
作者：
LOTTER, MG;RABE, WL;MINNAAR, PC
We developed an easy-to-operate computer program for the IBM personal computer to calculate, display and store in a database platelet kinetic data determined by analysis of the rate of clearance of radiolabeled blood platelets from the circulation. This was done by curve fitting using the weighted mean method and multiple-hit model. These models are complementary and calculating the mean platelet survival time with both is recommended. Improvement of the weighted mean method was investigated. The optimized weighting and fitting the exponential function with the Marquardt non-linear least squares method improved the weighted mean method. The weighted mean and multiple-hit model could take up to 2 minutes. Calculation of the mean platelet survival time using both models has the advantage that conditions when calculation of the mean platelet survival time would be invalid, can be detected. The compouter program will promote the valid comparison of results obtained at different institutions.
