Multilevel Analysis of Individual and Contextual Factors Associated with Polio Non-Vaccination in Africa: Further Analyses to Enhance Policy and Opportunity to Save More Lives.
Multilevel Analysis of Individual and Contextual Factors Associated with Polio Non-Vaccination in Africa: Further Analyses to Enhance Policy and Opportunity to Save More Lives.
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DOI：
10.3390/vaccines9070683
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发表时间：
2021-06-22
期刊：
影响因子：
7.8
通讯作者：
Wiysonge CS
中科院分区：
文献类型：
--
作者：
Uthman OA;Ndwandwe D;Uthman MMB;Yaya S;Wiysonge CS
背景资料：非洲在2020年被认证为无脊髓灰质炎，为了保持无脊髓灰质炎状态，非洲国家需要实现并保持最佳的常规脊髓灰质炎疫苗接种覆盖率。最佳小儿麻痹症疫苗接种覆盖率的一个指标是没有通过常规服务接种小儿麻痹症疫苗的儿童的流行率。这项研究的目的是审查与非洲未接种脊髓灰质炎疫苗有关的个人、社区和国家一级的因素。研究方法：我们对2010年以来在非洲收集的人口和健康调查数据进行了多变量多水平logistic回归分析。我们确定了来自32个国家（3级）的16，283个社区（2级）中的64，867名年龄在12-23个月（1级）的儿童。结果：未接种脊髓灰质炎疫苗的流行率从埃及的2.19%到几内亚的32.74%不等。我们发现以下因素是小儿麻痹症未接种疫苗几率增加的独立预测因素：是男孩，出生于没有受过正规教育的母亲，生活在较贫困的家庭;来自一夫多妻制家庭，生活在母亲文盲率高的社区，高失业率，以及接触媒体的机会少。结论：我们发现个人和环境因素都与未接种脊髓灰质炎疫苗有关。
Background: Africa was certified polio-free in 2020 and to maintain the polio-free status, African countries need to attain and maintain optimal routine polio vaccination coverage. One indicator for optimal polio vaccination coverage is the prevalence of children who have received no polio vaccination through routine services. The objective of the study was to examine the individual-, neighbourhood-, and country-level factors associated with non-vaccination against polio in Africa. Methods: We applied multivariable multilevel logistic regression analyses on recent demographic and health survey data collected from 2010 onwards in Africa. We identified 64,867 children aged 12–23 months (Level 1) nested within 16,283 neighbourhoods (Level 2) from 32 countries (Level 3). Results: The prevalence of non-vaccination for polio ranged from 2.19% in Egypt to 32.74% in Guinea. We found the following factors to be independent predictors of the increased odds of non-vaccination for polio: being a male child, born to mother with no formal education, living in poorer households; being from a polygamous family, living in neighbourhoods with high maternal illiteracy, high unemployment rate, and low access to media. Conclusions: We found that both individual and contextual factors are associated with non-vaccination for Polio.
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影响因子：
3.5
作者：
Filmer, D;Pritchett, LH
通讯作者：
Pritchett, LH
影响因子：
4.8
作者：
Uthman, Olalekan A.;Adedokun, Sulaimon T.;Wiysonge, Charles S.
通讯作者：
Wiysonge, Charles S.
影响因子：
2.1
作者：
Kravdal, Oystein
通讯作者：
Kravdal, Oystein
影响因子：
3.5
作者：
Montgomery, MR;Gragnolati, M;Paredes, E
通讯作者：
Paredes, E
影响因子：
3.2
作者：
Bryan, Mark L.;Jenkins, Stephen P.
通讯作者：
Jenkins, Stephen P.