DISSOCIATION OF OXYTOCIN, VASOPRESSIN AND CORTICOTROPIN SECRETION DURING DIFFERENT TYPES OF STRESS
DISSOCIATION OF OXYTOCIN, VASOPRESSIN AND CORTICOTROPIN SECRETION DURING DIFFERENT TYPES OF STRESS
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DOI：
10.1016/0024-3205(84)90241-8
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发表时间：
1984-01-01
期刊：
影响因子：
6.1
通讯作者：
GIBBS, DM
中科院分区：
文献类型：
--
作者：
GIBBS, DM
本研究测定了束缚、寒冷和乙醚3种应激模型中1种应激状态下雄性大鼠外周血浆中催产素（OT）、加压素（AVP）和促肾上腺皮质激素（ACTH）的含量。与未应激对照组相比，所有3组的ACTH分泌均增加。OT分泌增加大鼠受到约束或乙醚，但不冷。AVP分泌增加，只有乙醚应激。下丘脑和神经垂体对控制促肾上腺皮质激素分泌的贡献可能会因不同类型的应激而有所不同。
Oxytocin (OT), vasopressin (AVP) and ACTH levels were measured in peripheral plasma of male rats subjected to 1 of 3 models of stress: restraint, cold or ether. ACTH secretion was increased in all 3 groups compared to unstressed controls. OT secretion was increased in rats subjected to restraint or ether, but not cold. AVP secretion was increased only by ether stress. The hypothalamic and neurohypophyseal contribution to the control of ACTH secretion may vary in response to different types of stress.