Comparison of A1C and fasting glucose criteria to diagnose diabetes among U.S. adults.
Comparison of A1C and fasting glucose criteria to diagnose diabetes among U.S. adults.
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DOI：
10.2337/dc09-1227
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发表时间：
2010-01
期刊：
影响因子：
16.2
通讯作者：
Muntner P
中科院分区：
文献类型：
--
作者：
Carson AP;Reynolds K;Fonseca VA;Muntner P
比较A1 C和空腹血糖在美国成年人糖尿病诊断中的作用。本研究纳入了1999-2006年国家健康和营养检查调查中的6，890名成年人（≥20岁），他们没有自我报告的糖尿病史，禁食≥9小时。A1 C ≥6.5%和空腹血糖≥126 mg/dl分别用于定义糖尿病。总体而言，1.8%的美国成年人A1 C ≥6.5%且空腹血糖≥126 mg/dl，0.5%的人A1 C ≥6.5%且空腹血糖<126 mg/dl，1.8%的人A1 C <6.5%且空腹血糖≥126 mg/dl。与A1 C <6.5%和空腹血糖≥126 mg/dl的个体相比，A1 C ≥6.5%和空腹血糖<126 mg/dl的个体更年轻，更可能是非西班牙裔黑人，Hb水平较低，C反应蛋白较高。A1 C ≥6.5%与空腹血糖在美国成年人中诊断糖尿病的合理一致性。
To compare A1C and fasting glucose for the diagnosis of diabetes among U.S. adults. This study included 6,890 adults (≥20 years of age) from the 1999–2006 National Health and Nutrition Examination Survey without a self-reported history of diabetes who had fasted ≥9 h. A1C ≥6.5% and fasting glucose ≥126 mg/dl were used, separately, to define diabetes. Overall, 1.8% of U.S. adults had A1C ≥6.5% and fasting glucose ≥126 mg/dl, 0.5% had A1C ≥6.5% and fasting glucose <126 mg/dl, and 1.8% had A1C <6.5% and fasting glucose ≥126 mg/dl. Compared with individuals with A1C <6.5% and fasting glucose ≥126 mg/dl, individuals with A1C ≥6.5% and fasting glucose <126 mg/dl were younger, more likely to be non-Hispanic black, had lower Hb levels, and had higher C-reactive protein. A1C ≥6.5% demonstrates reasonable agreement with fasting glucose for diagnosing diabetes among U.S. adults.