PREDICTING FEMORAL-NECK STRENGTH FROM BONE-MINERAL DATA - A STRUCTURAL APPROACH
PREDICTING FEMORAL-NECK STRENGTH FROM BONE-MINERAL DATA - A STRUCTURAL APPROACH
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DOI：
10.1097/00004424-199001000-00004
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发表时间：
1990-01-01
影响因子：
6.7
通讯作者：
RAO, GU
中科院分区：
文献类型：
--
作者：
BECK, TJ;RUFF, CB;RAO, GU
开发了一个交互式计算机程序，从原始骨矿物质图像数据中推导出股骨颈几何形状，用于使用单平面工程应力分析估计髋关节强度。我们称之为髋关节强度分析（HSA）的程序是为了提高骨质疏松症骨折风险评估中髋骨矿物质数据的预测价值而开发的。我们报告了一系列的实验与铝幻影和尸体股骨，旨在测试的准确性，推导出的几何测量和强度估计。使用Lunar DP 3（DPA）和Hologic QDR-1000（X射线）扫描仪采集的数据，HSA计算的股骨颈横截面积（CSA）和横截惯性矩（CSMI）在铝体模上与实际值非常一致（r > .99）。使用Lunar DP 3数据，22具尸体股骨颈中段的CSA和CSMI测量值与文献值基本一致。HSA计算的横截面性质的三个标本进行了比较，从连续CT横截面图像的测量。沿股骨颈长度，两种方法之间的差异平均小于沿着10%。最后，用材料测试系统测量了20个股骨的断裂强度，显示出与HSA预测强度（r = .89，估计值的百分比标准（%SEE）= 21%）比股骨颈骨矿物质密度（r = .79，%SEE = 28%）更好的一致性。
An interactive computer program was developed to derive femoral neck geometry from raw bone mineral image data for an estimate of hip strength using single plane engineering stress analysis. The program, which we call Hip Strength Analysis (HSA), was developed as an attempt to improve the predictive value of hip bone mineral data for osteoporosis fracture risk assessment. We report a series of experiments with an aluminum phantom and with cadaver femora, designed to test the accuracy of derived geometric measurements and strength estimates. Using data acquired with both Lunar DP3 (DPA) and Hologic QDR-1000 (x-ray) scanners, HSA computed femoral neck cross-sectional areas (CSA) and cross-sectional moments of inertia (CSMI) on aluminum phantom were in excellent agreement with actual values (r > .99). Using Lunar DP3 data, CSA and CSMI measurements at midfemoral necks of 22 cadaver speciments were in good general agreement with literature values. HSA computed cross-sectional properties of three of these specimens were compared with measurements derived from sequential CT cross-sectional images. Discrepancy between the two methods averaged less than 10% along the length of the femoral neck. Finally, breaking strengths of 20 of the femora were measured with a materials testing system, showing better agreement with HSA predicted strength (r = .89, percent standard of the estimate (%SEE) = 21%) than femoral neck bone mineral density (r = .79, %SEE = 28%).